SUNITINIB INDUCED IMMUNE THROMBOCYTOPENIA (SHORT COMMUNICATION)

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SHEKARRIZ RAMIN; KOULAEINEJAD NEDA; NOSRATI ANAHITA; SALEHIFAR EBRAHIM

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Journal Paper

Paper Information

Journal: Iranian Journal of Pharmaceutical Research Year:2015 | Volume:14 | Issue:4 Page(s): 1295-1297

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Information Journal Paper

Title

SUNITINIB INDUCED IMMUNE THROMBOCYTOPENIA (SHORT COMMUNICATION)

Author(s)

SHEKARRIZ RAMIN | KOULAEINEJAD NEDA | NOSRATI ANAHITA | SALEHIFAR EBRAHIM | Issue Writer Certificate

Keywords

SUNITINIB

CARCINOMA

THROMBOCYTOPENIA

TYROSINE KINASE

Abstract

SUNITINIB is an oral TYROSINE KINASE inhibitor which prevents tumor growth and metastatic progression. It was approved for treatment of advanced renal cell cancer, gastrointestinal stromal tumor and advanced pancreatic neuroendocrine tumors. It has several adverse reactions on multi organ systems including hematologic system. Although the neutropenia and THROMBOCYTOPENIA commonly happens as Grade 3 or 4 abnormalities following bone marrow suppression, in the rare cases, the immune mediated abnormality may drive the SUNITINIB-induced hematologic disorder. In this report, we present a case of immune-mediated THROMBOCYTOPENIA induced by SUNITINIB. One month after first treatment cycle with SUNITINIB, leucopenia and THROMBOCYTOPENIA were occurred. The patient had a normal bone marrow aspiration and biopsy, the THROMBOCYTOPENIA was resistant to platelet transfusion which successfully was treated with prednisolone.

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APA: Copy

SHEKARRIZ, RAMIN, KOULAEINEJAD, NEDA, NOSRATI, ANAHITA, & SALEHIFAR, EBRAHIM. (2015). SUNITINIB INDUCED IMMUNE THROMBOCYTOPENIA (SHORT COMMUNICATION). IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), 14(4), 1295-1297. SID. https://sid.ir/paper/288379/en

Vancouver: Copy

SHEKARRIZ RAMIN, KOULAEINEJAD NEDA, NOSRATI ANAHITA, SALEHIFAR EBRAHIM. SUNITINIB INDUCED IMMUNE THROMBOCYTOPENIA (SHORT COMMUNICATION). IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)[Internet]. 2015;14(4):1295-1297. Available from: https://sid.ir/paper/288379/en

IEEE: Copy

RAMIN SHEKARRIZ, NEDA KOULAEINEJAD, ANAHITA NOSRATI, and EBRAHIM SALEHIFAR, “SUNITINIB INDUCED IMMUNE THROMBOCYTOPENIA (SHORT COMMUNICATION),” IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), vol. 14, no. 4, pp. 1295–1297, 2015, [Online]. Available: https://sid.ir/paper/288379/en

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