EVALUATION OF ANTI-INFLAMMATORY AND ANTI-NOCICEPTIVE EFFECTS OF DEFATTED FRUIT EXTRACT OF OLEA EUROPAEA

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SAHRANAVARD SHAMIM; KAMALINEJAD MOHAMMAD; FAIZI MEHRDAD

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Journal of Pharmaceutical Research Year:2014 | Volume:13 | Issue:SUPPL Page(s): 119-123

Download Full-Text

View:

262

Download:

122

Cites:

Information Journal Paper

Title

EVALUATION OF ANTI-INFLAMMATORY AND ANTI-NOCICEPTIVE EFFECTS OF DEFATTED FRUIT EXTRACT OF OLEA EUROPAEA

Author(s)

SAHRANAVARD SHAMIM | KAMALINEJAD MOHAMMAD | FAIZI MEHRDAD | Issue Writer Certificate

Keywords

OLEA EUROPAEA

ANTI-NOCICEPTIVE

ANTI-INFLAMMATORY

Abstract

Fruits of OLEA EUROPAEA L. have been used for centuries in folk medicine to treat many inflammatory diseases. In order to evaluate the ANTI-NOCICEPTIVE activities of the methanolic and aqueous extracts of defatted fruits of O. europaea, formalin test was used and for evaluation of ANTI-INFLAMMATORY effects of the extract, the volume of paw edema was measured. The results revealed that both extracts did not exhibit significant analgesic activity in the first phase of formalin test, whereas methanolic extract at the 600 mg/Kg dose and aqueous extract at the 450 and 600 mg/Kg doses could inhibit induced pain in the second phase of formalin test. Furthermore, the results of paw edema volume measurement indicated that the aqueous extract has ANTI-INFLAMMATORY effects at dose of 600 mg/Kg. Induced anti-nociception by aqueous olive extract was not reversed by naloxone, which indicates that the opioid receptors are not involved in the analgesic effects of the extracts. The present data pointed out that the extracts of olive defatted fruit have ANTI-NOCICEPTIVE and ANTI-INFLAMMATORY effects in rats but further studies are needed to elucidate the mechanism (s) of action and active components which are involved in analgesic and ANTI-INFLAMMATORY effects.

Cites

No record.

References

No record.

Cite

APA: Copy

SAHRANAVARD, SHAMIM, KAMALINEJAD, MOHAMMAD, & FAIZI, MEHRDAD. (2014). EVALUATION OF ANTI-INFLAMMATORY AND ANTI-NOCICEPTIVE EFFECTS OF DEFATTED FRUIT EXTRACT OF OLEA EUROPAEA. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), 13(SUPPL), 119-123. SID. https://sid.ir/paper/288420/en

Vancouver: Copy

SAHRANAVARD SHAMIM, KAMALINEJAD MOHAMMAD, FAIZI MEHRDAD. EVALUATION OF ANTI-INFLAMMATORY AND ANTI-NOCICEPTIVE EFFECTS OF DEFATTED FRUIT EXTRACT OF OLEA EUROPAEA. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)[Internet]. 2014;13(SUPPL):119-123. Available from: https://sid.ir/paper/288420/en

IEEE: Copy

SHAMIM SAHRANAVARD, MOHAMMAD KAMALINEJAD, and MEHRDAD FAIZI, “EVALUATION OF ANTI-INFLAMMATORY AND ANTI-NOCICEPTIVE EFFECTS OF DEFATTED FRUIT EXTRACT OF OLEA EUROPAEA,” IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), vol. 13, no. SUPPL, pp. 119–123, 2014, [Online]. Available: https://sid.ir/paper/288420/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops