The Effect of Wheat Germ Extract on Premenstrual Syndrome Symptoms

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ATAOLLAHI MARYAM; AMIR ALI AKBARI SEDIGHEH; MOJAB FARAZ; ALAVI MAJD HAMID

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Journal: Iranian Journal of Pharmaceutical Research Year:2015 | Volume:14 | Issue:1 Page(s): 159-166

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Title

The Effect of Wheat Germ Extract on Premenstrual Syndrome Symptoms

Author(s)

ATAOLLAHI MARYAM | AMIR ALI AKBARI SEDIGHEH | MOJAB FARAZ | ALAVI MAJD HAMID | Issue Writer Certificate

Keywords

Premenstrual syndrome

Wheat germ extract

Menstrual disorders

Herbal medicine

Abstract

Pre-menstrual syndrome is one of the most common disorders in women and impairs work and social relationships. Several treatment modalities have been proposed including Herbal medicines. Considering the properties of wheat germ, this study aimed to determine the effects of Wheat germ extract on the symptoms of Premenstrual syndrome. This triple blind clinical trial was conducted on 84 women working in hospitals affiliated to Hamadan University of Medical Sciences. Subjects completed daily symptom record form for two consecutive months. After definitive diagnosis of Premenstrual syndrome, they were randomly divided into two groups of 50 people. Then, for two consecutive months, 400 mg capsules of Wheat germ extract or placebo were used three times a day, from day 16 until day 5 of the next menstrual cycle. Wheat germ significantly reduced physical symptoms (63. 56%), psychological symptoms (66. 30%), and the general score (64. 99%). Although the severity of symptoms decreased in both groups, this reduction was more significant in the Wheat germ extract group (p < 0. 001). On the other hand, physical symptoms decreased only in the Wheat germ extract (p < 0. 001) and there was no statistically significant difference in the placebo group. No complications were observed in any of the groups. It seems that using Wheat germ extract reduces general, psychological and physical symptoms.

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APA: Copy

ATAOLLAHI, MARYAM, AMIR ALI AKBARI, SEDIGHEH, MOJAB, FARAZ, & ALAVI MAJD, HAMID. (2015). The Effect of Wheat Germ Extract on Premenstrual Syndrome Symptoms. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), 14(1), 159-166. SID. https://sid.ir/paper/288508/en

Vancouver: Copy

ATAOLLAHI MARYAM, AMIR ALI AKBARI SEDIGHEH, MOJAB FARAZ, ALAVI MAJD HAMID. The Effect of Wheat Germ Extract on Premenstrual Syndrome Symptoms. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)[Internet]. 2015;14(1):159-166. Available from: https://sid.ir/paper/288508/en

IEEE: Copy

MARYAM ATAOLLAHI, SEDIGHEH AMIR ALI AKBARI, FARAZ MOJAB, and HAMID ALAVI MAJD, “The Effect of Wheat Germ Extract on Premenstrual Syndrome Symptoms,” IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), vol. 14, no. 1, pp. 159–166, 2015, [Online]. Available: https://sid.ir/paper/288508/en

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