Dynamic Variation Patterns of Aconitum Alkaloids in Daughter Root of Aconitum Carmichaelii (Fuzi) in the Decoction Process Based on the Content Changes of Nine Aconitum Alkaloids by HPLC-MS-MS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Luo Heng; Huang Zhifang; Xiaolong; Yi Jinhai; Chen Shuiying; Yang Andong; YANG JUN

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Journal of Pharmaceutical Research Year:2016 | Volume:15 | Issue:1 Page(s): 263-273

Download Full-Text

View:

198

Download:

142

Cites:

Information Journal Paper

Title

Dynamic Variation Patterns of Aconitum Alkaloids in Daughter Root of Aconitum Carmichaelii (Fuzi) in the Decoction Process Based on the Content Changes of Nine Aconitum Alkaloids by HPLC-MS-MS

Author(s)

Keywords

Fuzi

Aconite decoction

Aconitum alkaloids

Dynamic variation

HPLC-MSMS

Abstract

The chemical components in the decoctions of Chinese herbal medicines are not always the same as those in the crude herbs because of the insolubility or instability of some compounds. In this work, a high-performance liquid chromatography (HPLC) coupled with electrospray ionization (ESI) tandem mass spectrometry method was developed to explore Dynamic variation patterns of Aconitum alkaloids in Fuzi during the process of decocting aconite root. The fragmentation patterns of Aconitum alkaloids using ESI and collision-induced dissociation (CID) techniques were reported. This assay method was validated with respect to linearity (r2 > 0. 9950), precision, repeatability, and accuracy (recovery rate between 94. 6 and 107. 9%). The result showed that the amounts of Aconitum alkaloids in the decoction at different boiling time varied significantly. In the decoction process, the diester-type alkaloids in crude aconite roots have transformed into Benzoylaconines or aconines.

Cites

No record.

References

No record.

Cite

APA: Copy

Luo, Heng, Huang, Zhifang, , Xiaolong, Yi, Jinhai, Chen, Shuiying, Yang, Andong, & YANG, JUN. (2016). Dynamic Variation Patterns of Aconitum Alkaloids in Daughter Root of Aconitum Carmichaelii (Fuzi) in the Decoction Process Based on the Content Changes of Nine Aconitum Alkaloids by HPLC-MS-MS. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), 15(1), 263-273. SID. https://sid.ir/paper/288532/en

Vancouver: Copy

Luo Heng, Huang Zhifang, Xiaolong, Yi Jinhai, Chen Shuiying, Yang Andong, YANG JUN. Dynamic Variation Patterns of Aconitum Alkaloids in Daughter Root of Aconitum Carmichaelii (Fuzi) in the Decoction Process Based on the Content Changes of Nine Aconitum Alkaloids by HPLC-MS-MS. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)[Internet]. 2016;15(1):263-273. Available from: https://sid.ir/paper/288532/en

IEEE: Copy

Heng Luo, Zhifang Huang, Xiaolong , Jinhai Yi, Shuiying Chen, Andong Yang, and JUN YANG, “Dynamic Variation Patterns of Aconitum Alkaloids in Daughter Root of Aconitum Carmichaelii (Fuzi) in the Decoction Process Based on the Content Changes of Nine Aconitum Alkaloids by HPLC-MS-MS,” IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), vol. 15, no. 1, pp. 263–273, 2016, [Online]. Available: https://sid.ir/paper/288532/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops