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Information Journal Paper

Title

EFFECT OF MELISSA OFFICINALIS (LEMON BALM) ON SEXUAL DYSFUNCTION IN WOMEN: A DOUBLE- BLIND, RANDOMIZED, PLACEBO-CONTROLLED STUDY

Pages

  89-100

Abstract

HYPOACTIVE SEXUAL DESIRE DISORDER (HSDD) is the most prevalent female SEXUAL DYSFUNCTION(FSD) and its bio-psychosocial multifactorial etiology justifies its multifaceted treatment. In PERSIAN MEDICINE (PM), the weakness of the main organs (heart, brain and liver) is one of the important causes of lack of sexual desire; hence, their strengthening is a priority during treatment. Melissa officinalis is one of the medicinal plants with tonic characteristics for the main organs in PM and was used for treatment in this study. The aim of the present study was to evaluate the efficacy and safety of M. officinalis in the improvement of HSDD in WOMEN. Eighty nine (89) eligible WOMEN suffering from decreased sexual desire were randomly assigned to groups. The participants received medication (500 mg of aqueous extract of M. officinalis) or placebo 2 times a day for 4 weeks. Changes in scores of desire, arousal, lubrication, orgasm, satisfaction and pain were evaluated at the end of 4 weeks of treatment using the Female Sexual Function Index (FSFI) questionnaire in the two groups. Forty three participants completed the study. The increase in desire (P<0.001), arousal (P<0.001), lubrication (P<0.005), orgasm (P<0.001), satisfaction (P<0.001), pain (P<0.002) and FSFI total score (P<0.001) in the M. officinalis group was significantly more than that of the placebo group. The willingness to continue treatment was significantly higher in the M. officinalis as compared to the placebo group (P<0.001). M. officinalis may be a safe and effective herbal medicine for the improvement of HSDD in WOMEN.

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    APA: Copy

    DARVISH MOFRAD KASHANI, ZAHRA, EMARATKAR, ELHAM, HASHEM DABAGHIAN, FATANEH, EMADI, FATEMEH, RAISI, FIROOZEH, ALIASL, JALE, KAMALINEJAD, MOHAMMAD, HASHEMINEJAD, SEYED ABBAS, EFTEKHAR, TAHEREH, & ZAFARGHANDI, NAFISEH. (2018). EFFECT OF MELISSA OFFICINALIS (LEMON BALM) ON SEXUAL DYSFUNCTION IN WOMEN: A DOUBLE- BLIND, RANDOMIZED, PLACEBO-CONTROLLED STUDY. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), 17(SUPPLEMENT), 89-100. SID. https://sid.ir/paper/288798/en

    Vancouver: Copy

    DARVISH MOFRAD KASHANI ZAHRA, EMARATKAR ELHAM, HASHEM DABAGHIAN FATANEH, EMADI FATEMEH, RAISI FIROOZEH, ALIASL JALE, KAMALINEJAD MOHAMMAD, HASHEMINEJAD SEYED ABBAS, EFTEKHAR TAHEREH, ZAFARGHANDI NAFISEH. EFFECT OF MELISSA OFFICINALIS (LEMON BALM) ON SEXUAL DYSFUNCTION IN WOMEN: A DOUBLE- BLIND, RANDOMIZED, PLACEBO-CONTROLLED STUDY. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)[Internet]. 2018;17(SUPPLEMENT):89-100. Available from: https://sid.ir/paper/288798/en

    IEEE: Copy

    ZAHRA DARVISH MOFRAD KASHANI, ELHAM EMARATKAR, FATANEH HASHEM DABAGHIAN, FATEMEH EMADI, FIROOZEH RAISI, JALE ALIASL, MOHAMMAD KAMALINEJAD, SEYED ABBAS HASHEMINEJAD, TAHEREH EFTEKHAR, and NAFISEH ZAFARGHANDI, “EFFECT OF MELISSA OFFICINALIS (LEMON BALM) ON SEXUAL DYSFUNCTION IN WOMEN: A DOUBLE- BLIND, RANDOMIZED, PLACEBO-CONTROLLED STUDY,” IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), vol. 17, no. SUPPLEMENT, pp. 89–100, 2018, [Online]. Available: https://sid.ir/paper/288798/en

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