EVALUATION OF VARIOUS BIOLOGICAL ACTIVITIES OF THE AERIAL PARTS OF SCROPHULARIA FRIGIDA GROWING IN IRAN

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

ASGHARIAN PARINA; HESHMATI AFSHAR FARIBA; ASNAASHARI SOLMAZ; LOTFIPOUR FARZANEH; BARADARAN BEHZAD; ZOLALI ELMIRA; NIKKHAH ELHAMEH; DELAZAR ABBAS

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Journal of Pharmaceutical Research Year:2017 | Volume:16 | Issue:1 Page(s): 277-289

Download Full-Text

View:

206

Download:

176

Cites:

Information Journal Paper

Title

EVALUATION OF VARIOUS BIOLOGICAL ACTIVITIES OF THE AERIAL PARTS OF SCROPHULARIA FRIGIDA GROWING IN IRAN

Author(s)

Keywords

SCROPHULARIA FRIGIDA

ANTIOXIDANT ACTIVITY

CYTOTOXIC EFFECT

PHYTOCHEMICAL ANALYSIS

NMR

GC-MS

Abstract

The current study was assigned to evaluate the total phenol, total flavonoid content (TPC, TFC) and antioxidant properties of extracts from the aerial parts of SCROPHULARIA FRIGIDA (S. frigida). Extracts were also tested by preliminary phytochemical screening as well as cytotoxic activity against Artemia salina, MCF-7 (human breast carcinoma) and SW-480 (colon carcinoma) and L-929 (normal) cell lines along with antimicrobial characteristic. DPPH, MTT and Brine shrimp lethality tests and disc diffusion method were carried out to determine the biological activities of the different extracts of S. frigida. In addition, the extracts which had more potent antioxidant and antiproliferative activity were further analyzed by NMR and GC-MS.40% methanol-water (from MeOH extract) fraction showed higher amounts of TPC, TFC and antioxidant property. Findings of the study for general toxicity effect showed that dichloromethane (DCM) and MeOH extracts had weak to moderate effects. Furthermore, DCM extract indicated the most potent anti- proliferative activity against cancer cell lines. No evidence of antibacterial activity was determined. On the other hand, analysis of the potent extract DCM in cytotoxic assay showed the presence of trans- phytol and cis- oleic acid in GC-MS. Furthermore, NMR analysis of potent methanolic fractions in antioxidant tests revealed the presence of iridoids and phenolics. Generally, the results of TPC, TFC and ANTIOXIDANT ACTIVITY of extracts and fractions were in agreement with each other.

Cites

No record.

References

No record.

Cite

APA: Copy

ASGHARIAN, PARINA, HESHMATI AFSHAR, FARIBA, ASNAASHARI, SOLMAZ, LOTFIPOUR, FARZANEH, BARADARAN, BEHZAD, ZOLALI, ELMIRA, NIKKHAH, ELHAMEH, & DELAZAR, ABBAS. (2017). EVALUATION OF VARIOUS BIOLOGICAL ACTIVITIES OF THE AERIAL PARTS OF SCROPHULARIA FRIGIDA GROWING IN IRAN. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), 16(1), 277-289. SID. https://sid.ir/paper/288806/en

Vancouver: Copy

ASGHARIAN PARINA, HESHMATI AFSHAR FARIBA, ASNAASHARI SOLMAZ, LOTFIPOUR FARZANEH, BARADARAN BEHZAD, ZOLALI ELMIRA, NIKKHAH ELHAMEH, DELAZAR ABBAS. EVALUATION OF VARIOUS BIOLOGICAL ACTIVITIES OF THE AERIAL PARTS OF SCROPHULARIA FRIGIDA GROWING IN IRAN. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)[Internet]. 2017;16(1):277-289. Available from: https://sid.ir/paper/288806/en

IEEE: Copy

PARINA ASGHARIAN, FARIBA HESHMATI AFSHAR, SOLMAZ ASNAASHARI, FARZANEH LOTFIPOUR, BEHZAD BARADARAN, ELMIRA ZOLALI, ELHAMEH NIKKHAH, and ABBAS DELAZAR, “EVALUATION OF VARIOUS BIOLOGICAL ACTIVITIES OF THE AERIAL PARTS OF SCROPHULARIA FRIGIDA GROWING IN IRAN,” IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), vol. 16, no. 1, pp. 277–289, 2017, [Online]. Available: https://sid.ir/paper/288806/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops