مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Cites:

1

Information Journal Paper

Title

THE EFFECTS OF TRANSDERMAL ESTROGEN DELIVERY ON BONE MINERAL DENSITY IN POSTMENOPAUSAL WOMEN: A META- ANALYSIS

Pages

  380-389

Abstract

 Due to its minimal systematic adverse effects, TRANSDERMAL ESTROGEN is widely used for the prevention of osteoporosis in postmenopausal women. The present meta-analysis aimed to clarify the effects of TRANSDERMAL ESTROGEN on BONE MINERAL DENSITY (BMD) of postmenopausal women. Studies were identified by searching electronic databases including Cochrane Library, MEDLINE, Embase, and CINAHL databases, and also the Sciences Citation Index. Systematic review of articles was published between January 1989 to February 2016.Reference lists of the included articles were also evaluated and consultations were made with relevant experts. While 132 studies included the desired keywords, only nine clinical trials met the inclusion criteria and were finally reviewed. The pooled percent change in BMD was statistically significant in favor of TRANSDERMAL ESTROGEN. According to resulting pooled estimate, lumbar spine BMD one and two years after TRANSDERMAL ESTROGEN therapy was respectively 3.4% (95% CI: 1.7-5.1) and 3.7% (95% CI: 1.7-5.7) higher than the baseline values. The test for heterogeneity was not statistically significant based on the I2 heterogeneity index. One-two years of TRANSDERMAL ESTROGEN delivery can effectively increase BMD and protect the bone structure in postmenopausal women.

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    APA: Copy

    ABDI, FATEMEH, MOBEDI, HAMID, BAYAT, FARHAD, MOSAFFA, NARIMAN, DOLATIAN, MAHROKH, & RAMEZANI TEHRANI, FAHIMEH. (2017). THE EFFECTS OF TRANSDERMAL ESTROGEN DELIVERY ON BONE MINERAL DENSITY IN POSTMENOPAUSAL WOMEN: A META- ANALYSIS. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), 16(1), 380-389. SID. https://sid.ir/paper/288826/en

    Vancouver: Copy

    ABDI FATEMEH, MOBEDI HAMID, BAYAT FARHAD, MOSAFFA NARIMAN, DOLATIAN MAHROKH, RAMEZANI TEHRANI FAHIMEH. THE EFFECTS OF TRANSDERMAL ESTROGEN DELIVERY ON BONE MINERAL DENSITY IN POSTMENOPAUSAL WOMEN: A META- ANALYSIS. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)[Internet]. 2017;16(1):380-389. Available from: https://sid.ir/paper/288826/en

    IEEE: Copy

    FATEMEH ABDI, HAMID MOBEDI, FARHAD BAYAT, NARIMAN MOSAFFA, MAHROKH DOLATIAN, and FAHIMEH RAMEZANI TEHRANI, “THE EFFECTS OF TRANSDERMAL ESTROGEN DELIVERY ON BONE MINERAL DENSITY IN POSTMENOPAUSAL WOMEN: A META- ANALYSIS,” IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), vol. 16, no. 1, pp. 380–389, 2017, [Online]. Available: https://sid.ir/paper/288826/en

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