مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

196
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

101
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

EXPOSING THE MOLECULAR SCREENING METHOD OF INDONESIAN NATURAL PRODUCTS DERIVATE AS DRUG CANDIDATES FOR CERVICAL CANCER

Author(s)

 FRIEND TAMBUNAN USMAN SUMO | PARIKESIT ARLI ADITYA | FARDIANSYAH NASUTION MOCHAMMAD ARFIN | HAPSARI AMALIA | KERAMI DJATI | Issue Writer Certificate 

Pages

  1113-1127

Abstract

 The menace of CERVICAL CANCER has reached an alarming rate. There are more than 450. 000cases of CERVICAL CANCER yearly, with mortality rate of about 50%. This deadly cancer is causedby human papillomavirus (HPV), mainly subtypes 16 and 18. The pharmaceutical industryhas produced drug for combating the virus, known as SAHA (suberoylanilide hydroxamicacid). It inhibits class II HDAC Homo sapiens (HDACi). The utilization of SAHA has someside effects, one of which is bone loss. Thus, searching for viable alternatives aside SAHA isinevitable. The objective of this research is to investigate the molecular interaction of selectedINDONESIAN NATURAL PRODUCTS with class II HDAC Homo sapiens. LigX tool in MOE 2008. 10was used as an instrument to investigate the molecular interaction. Then, computer-aided drugdiscovery and development (CADDD) approach involving molecular docking and dynamicsmethods was utilized to screen the natural products library. In the end, we found that herbaricacid could act as a potential drug candidate for CERVICAL CANCER.

Cites

  • No record.

    • References

  • No record.

    • Cite

    APA: Copy

    FRIEND TAMBUNAN, USMAN SUMO, PARIKESIT, ARLI ADITYA, FARDIANSYAH NASUTION, MOCHAMMAD ARFIN, HAPSARI, AMALIA, & KERAMI, DJATI. (2017). EXPOSING THE MOLECULAR SCREENING METHOD OF INDONESIAN NATURAL PRODUCTS DERIVATE AS DRUG CANDIDATES FOR CERVICAL CANCER. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), 16(3), 1113-1127. SID. https://sid.ir/paper/288990/en

    Vancouver: Copy

    FRIEND TAMBUNAN USMAN SUMO, PARIKESIT ARLI ADITYA, FARDIANSYAH NASUTION MOCHAMMAD ARFIN, HAPSARI AMALIA, KERAMI DJATI. EXPOSING THE MOLECULAR SCREENING METHOD OF INDONESIAN NATURAL PRODUCTS DERIVATE AS DRUG CANDIDATES FOR CERVICAL CANCER. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)[Internet]. 2017;16(3):1113-1127. Available from: https://sid.ir/paper/288990/en

    IEEE: Copy

    USMAN SUMO FRIEND TAMBUNAN, ARLI ADITYA PARIKESIT, MOCHAMMAD ARFIN FARDIANSYAH NASUTION, AMALIA HAPSARI, and DJATI KERAMI, “EXPOSING THE MOLECULAR SCREENING METHOD OF INDONESIAN NATURAL PRODUCTS DERIVATE AS DRUG CANDIDATES FOR CERVICAL CANCER,” IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), vol. 16, no. 3, pp. 1113–1127, 2017, [Online]. Available: https://sid.ir/paper/288990/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button