مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

BIOSYNTHESIS, CHARACTERIZATION, ANTIMICROBIAL AND CYTOTOXIC EFFECTS OF SILVER NANOPARTICLES USING NIGELLA ARVENSIS SEED EXTRACT

Pages

  1167-1175

Abstract

 The biogenic synthesis of metal nanomaterial offers an environmentally benign alternativeto the traditional chemical synthesis routes. In the present study, the green synthesis of silvernanoparticles (AgNPs) from aqueous solution of silver nitrate (AgNO3) by using Nigellaarvensis L. seed powder extract (NSPE) has been reported. AgNPs were characterized byUV– vis absorption spectroscopy with an intense surface plasmon resonance band at 435 nmwhich reveals the formation of nanoparticles. Fourier transmission infrared spectroscopy(FTIR) showed that nanoparticles were capped with plant compounds. Transmission electronmicroscopy (TEM) showed silver nanoparticles, with a size of 2-15 nm, were spherical. TheX-ray diffraction spectrum (XRD) pattern clearly indicates that AgNPs formed in the presentsynthesis were crystalline in nature. Stabilized films of exudate synthesized AgNPs wereeffective anti-bacterial agents. In addition, these biologically synthesized nanoparticles werealso proved to exhibit excellent cytotoxic effect on a human breast cancer cell line (MCF-7) and a human colorectal adenocarcinoma cell line (HT-29). The results confirmed that theNSPE is a very good ecofriendly and nontoxic source for the synthesis of AgNPs as comparedto the conventional chemical/physical methods. Therefore, N. arvensis seed provides futureopportunities in nanomedicine by tagging nanoparticles with secondary metabolites.

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    APA: Copy

    CHAHARDOLI, AZAM, KARIMI, NASER, & fattahi, ali. (2017). BIOSYNTHESIS, CHARACTERIZATION, ANTIMICROBIAL AND CYTOTOXIC EFFECTS OF SILVER NANOPARTICLES USING NIGELLA ARVENSIS SEED EXTRACT. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), 16(3), 1167-1175. SID. https://sid.ir/paper/289000/en

    Vancouver: Copy

    CHAHARDOLI AZAM, KARIMI NASER, fattahi ali. BIOSYNTHESIS, CHARACTERIZATION, ANTIMICROBIAL AND CYTOTOXIC EFFECTS OF SILVER NANOPARTICLES USING NIGELLA ARVENSIS SEED EXTRACT. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)[Internet]. 2017;16(3):1167-1175. Available from: https://sid.ir/paper/289000/en

    IEEE: Copy

    AZAM CHAHARDOLI, NASER KARIMI, and ali fattahi, “BIOSYNTHESIS, CHARACTERIZATION, ANTIMICROBIAL AND CYTOTOXIC EFFECTS OF SILVER NANOPARTICLES USING NIGELLA ARVENSIS SEED EXTRACT,” IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), vol. 16, no. 3, pp. 1167–1175, 2017, [Online]. Available: https://sid.ir/paper/289000/en

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