Radioprotective Effect of Thymol Against Salivary Glands Dysfunction Induced by Ionizing Radiation in Rats

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

ABEDI SEYED MOHAMMAD; YARMAND FATEME; MOTALLEBNEJAD MINA; SEYEDMAJIDI MARYAM; MOSLEMI DARIUSH; BIJANI ALI; HOSSEINIMEHR SEYED JALAL

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Journal of Pharmaceutical Research Year:2016 | Volume:15 | Issue:4 Page(s): 861-866

Download Full-Text

View:

203

Download:

105

Cites:

Information Journal Paper

Title

Radioprotective Effect of Thymol Against Salivary Glands Dysfunction Induced by Ionizing Radiation in Rats

Author(s)

Keywords

Thymol;

Radioprotective;

Salivary gland dysfunction;

Scintigraphy;

Radiotherapy

Abstract

The aim of this study was to investigate the radioprotective effect of thymol as a natural product against salivary glands dysfunction induced by ionizing radiation in rats. The rats were treated with thymol at dose of 50 mg/Kg before exposure to ionizing radiation at dose 15 Gy. Salivary gland function was evaluated with radioisotope scintigraphy and then salivary gland to background counts ratio was calculated. Ionizing radiation caused significant salivary glands dysfunction at the 3th and the 70th days with reduction in radioactivity uptake in salivary glands. Ratios of salivary gland to background radioactivities were 2. 0 ± 0. 05, 1. 58 ± 0. 62 and 1. 99 ± 0. 07 at 3th days for control, radiation, and thymol plus radiation groups, respectively. Thymol significantly protected acute and chronic salivary gland dysfunction induced by ionizing radiation in the rats. This finding may have been a promising application of thymol for the protection of salivary glands dysfunction induced by ionizing irradiation in patients exposed to radiation in head and neck cancer therapy.

Cites

No record.

References

No record.

Cite

APA: Copy

ABEDI, SEYED MOHAMMAD, YARMAND, FATEME, MOTALLEBNEJAD, MINA, SEYEDMAJIDI, MARYAM, MOSLEMI, DARIUSH, BIJANI, ALI, & HOSSEINIMEHR, SEYED JALAL. (2016). Radioprotective Effect of Thymol Against Salivary Glands Dysfunction Induced by Ionizing Radiation in Rats. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), 15(4), 861-866. SID. https://sid.ir/paper/289052/en

Vancouver: Copy

ABEDI SEYED MOHAMMAD, YARMAND FATEME, MOTALLEBNEJAD MINA, SEYEDMAJIDI MARYAM, MOSLEMI DARIUSH, BIJANI ALI, HOSSEINIMEHR SEYED JALAL. Radioprotective Effect of Thymol Against Salivary Glands Dysfunction Induced by Ionizing Radiation in Rats. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)[Internet]. 2016;15(4):861-866. Available from: https://sid.ir/paper/289052/en

IEEE: Copy

SEYED MOHAMMAD ABEDI, FATEME YARMAND, MINA MOTALLEBNEJAD, MARYAM SEYEDMAJIDI, DARIUSH MOSLEMI, ALI BIJANI, and SEYED JALAL HOSSEINIMEHR, “Radioprotective Effect of Thymol Against Salivary Glands Dysfunction Induced by Ionizing Radiation in Rats,” IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), vol. 15, no. 4, pp. 861–866, 2016, [Online]. Available: https://sid.ir/paper/289052/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops