Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

192
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

87
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

Does Regular Use of a Complementary Medicine of Olea Europe and Ficus carica Have Adverse Effects on Lipid Profile and Fasting Blood Glucose of Rheumatoid Arthritis (RA) Patients Under Treatment with DMARD Regimens Containing Methotrexate?

Pages

  933-940

Abstract

 Rheumatoid arthritis (RA) patients are vulnerable to cardiovascular morbidity and mortality in which atherosclerosis plays a major role. In this study, the lipid profile and fasting blood sugar (FBS) of RA patients receiving a complementary medicine of olive and Fig, as add-on therapy for routine disease-modifying antirheumatic drugs (DMARDs) regimen containing low dose methotrexate (MTX), were studied. A randomized controlled clinical trial was designed. Adult RA patients were randomly allocated in two groups receiving routine DMARDs regimen (control group) and routine DMARDs regimen plus the herbal supplementary formulation of olive oil, Fig and olive fruits (intervention group). Patients were followed every 4 weeks for total study period of 16 weeks. In addition to demographic and medical history of the patients, the total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), triglyceride (TG), the atherogenic index of plasma (AIP) defined as log(TG/HDL-C), and the fasting blood sugar (FBS) were determined and recorded. 56 patients (control = 27 and intervention = 29), with mean ± sd age of 50. 9 ± 12. 3 years completed the study. Average MTX dose received by intervention and control groups were 24. 30 ± 18. 39 and 17. 61 ± 15. 53 mg/week, respectively (p = 0. 11). Repeated measures analysis of variance (ANOVA) revealed that differences between lipid profile indicators and FBS in the two study groups were not statistically significant (P>0. 05). No additional substantial adverse reaction was seen in the study groups. Our findings are more reassuring for patients and their doctors to trust on the safety of the investigated complementary preparation to be used as add-on therapy to manage rheumatoid arthritis.

Cites

  • No record.

    • References

  • No record.

    • Cite

    APA: Copy

    Bahadori, Shahnaz, AHMADZADEH, ARMAN, SHAMS ARDEKANI, MOHAMMAD REZA, KAMALINEJAD, MOHAMMAD, KESHAVARZ, MANSOOR, & SALAMZADEH, JAMSHID. (2016). Does Regular Use of a Complementary Medicine of Olea Europe and Ficus carica Have Adverse Effects on Lipid Profile and Fasting Blood Glucose of Rheumatoid Arthritis (RA) Patients Under Treatment with DMARD Regimens Containing Methotrexate?. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), 15(4), 933-940. SID. https://sid.ir/paper/289060/en

    Vancouver: Copy

    Bahadori Shahnaz, AHMADZADEH ARMAN, SHAMS ARDEKANI MOHAMMAD REZA, KAMALINEJAD MOHAMMAD, KESHAVARZ MANSOOR, SALAMZADEH JAMSHID. Does Regular Use of a Complementary Medicine of Olea Europe and Ficus carica Have Adverse Effects on Lipid Profile and Fasting Blood Glucose of Rheumatoid Arthritis (RA) Patients Under Treatment with DMARD Regimens Containing Methotrexate?. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)[Internet]. 2016;15(4):933-940. Available from: https://sid.ir/paper/289060/en

    IEEE: Copy

    Shahnaz Bahadori, ARMAN AHMADZADEH, MOHAMMAD REZA SHAMS ARDEKANI, MOHAMMAD KAMALINEJAD, MANSOOR KESHAVARZ, and JAMSHID SALAMZADEH, “Does Regular Use of a Complementary Medicine of Olea Europe and Ficus carica Have Adverse Effects on Lipid Profile and Fasting Blood Glucose of Rheumatoid Arthritis (RA) Patients Under Treatment with DMARD Regimens Containing Methotrexate?,” IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), vol. 15, no. 4, pp. 933–940, 2016, [Online]. Available: https://sid.ir/paper/289060/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top