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Information Journal Paper

Title

Exposure to Aflatoxin M1 through Milk Consumption in Tehran Population, Iran

Author(s)

 Khaneghahi Abyaneh Hamid | BAHONAR ALIREZA | NOORI NEGIN | YAZDANPANAH HASSAN | Shojaee AliAbadi Mohammad Hossein | Issue Writer Certificate 

Pages

  1332-1340

Abstract

 Milk would be contaminated with Aflatoxin M1 (AFM1), if it was obtained from lactating animal which fed with feedstuffs containing Aflatoxin B1 (AFB1). AFM1 is classified as group 2B, possibly carcinogenic to humans and its exposure to AFM1 through Milk consumption is a public concern. The purpose of this study was to determine the AFM1 exposure through liquid Milk consumption for adult consumers in Tehran. Forty-five samples including raw, pasteurized, and UHT Milk samples were collected from markets in different cities of Tehran province in January and February 2017. The AFM1 was determined by HPLC method after immunoaffinity column clean up. Also, the Milk intake was calculated using household budget survey. Finally, the daily intake of AFM1 through Milk consumption was estimated using a deterministic approach. From total 45 samples, AFM1 was detected in 36 (80%) samples, although none of the analyzed samples were exceeded Iran legal limit of 0. 1 μ g/kg. On the basis of the average Milk intake, the mean daily exposure to AFM1 was estimated between 0. 03 ng/ Kg BW per day (lower bound estimate) and 0. 06 ng/ Kg BW per day (upper bound estimate) and the 95th percentile daily exposure was calculated at 0. 14 ng/ Kg BW per day. According to these values, it should be expected that the adults of Tehran population are not exposed to a significant risk of Hepatocarcinoma associated with AFM1 intake through Milk consumption.

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    APA: Copy

    Khaneghahi Abyaneh, Hamid, BAHONAR, ALIREZA, NOORI, NEGIN, YAZDANPANAH, HASSAN, & Shojaee AliAbadi, Mohammad Hossein. (2019). Exposure to Aflatoxin M1 through Milk Consumption in Tehran Population, Iran. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), 18(3), 1332-1340. SID. https://sid.ir/paper/289144/en

    Vancouver: Copy

    Khaneghahi Abyaneh Hamid, BAHONAR ALIREZA, NOORI NEGIN, YAZDANPANAH HASSAN, Shojaee AliAbadi Mohammad Hossein. Exposure to Aflatoxin M1 through Milk Consumption in Tehran Population, Iran. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)[Internet]. 2019;18(3):1332-1340. Available from: https://sid.ir/paper/289144/en

    IEEE: Copy

    Hamid Khaneghahi Abyaneh, ALIREZA BAHONAR, NEGIN NOORI, HASSAN YAZDANPANAH, and Mohammad Hossein Shojaee AliAbadi, “Exposure to Aflatoxin M1 through Milk Consumption in Tehran Population, Iran,” IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), vol. 18, no. 3, pp. 1332–1340, 2019, [Online]. Available: https://sid.ir/paper/289144/en

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