Comparative Study of the Effects of Chamomile (Matricaria Chamomilla L. ) and Cabergoline on Idiopathic Hyperprolactinemia: A Pilot Randomized Controlled Trial

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Kabiri Marya; KAMALINEJAD MOHAMMAD; BIOOS SOODABEH; SHARIAT MAMAK; SOHRABVAND FARNAZ

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Journal Paper

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Journal: Iranian Journal of Pharmaceutical Research Year:2019 | Volume:18 | Issue:3 Page(s): 1612-1621

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Title

Comparative Study of the Effects of Chamomile (Matricaria Chamomilla L. ) and Cabergoline on Idiopathic Hyperprolactinemia: A Pilot Randomized Controlled Trial

Author(s)

Keywords

Hyperprolactinemia

Matricaria chamomilla

Cabergoline

Prolactin

Complementary medicine

Chamomile

Abstract

Chamomile is a fascinating plant quoted in several traditional medicine texts, which has broad-spectrum pharmacological activity and medicinal uses. The aim of this study was to assess the efficacy of Chamomile syrup in reducing serum Prolactin in women with idiopathic Prolactinemia/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank">HyperProlactinemia. The study was a randomized, controlled clinical trial that was conducted on 56 women with idiopathic Prolactinemia/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank">HyperProlactinemia for a study period of four weeks. Patients were randomly enrolled in two parallel arms and were treated by Chamomile syrup at a dose of 5 mL twice daily or Cabergoline tablet orally at a dose of 0. 25 mg twice weekly. Serum Prolactin levels were measured at baseline and the end of the 4-week study period. Any report of adverse events was also recorded. Results revealed that within the Cabergoline group the reduction in the mean Prolactin level was significantly greater than that of the Chamomile group (p <0. 0001). It was also found that decline in the mean Prolactin level was statistically significant within the Chamomile group (p <0. 0001). Chamomile syrup seems to be effective on serum Prolactin reduction in women with idiopathic Prolactinemia/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank">HyperProlactinemia. However, studies with a larger sample size and for a longer follow-up period are recommended.

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APA: Copy

Kabiri, Marya, KAMALINEJAD, MOHAMMAD, BIOOS, SOODABEH, SHARIAT, MAMAK, & SOHRABVAND, FARNAZ. (2019). Comparative Study of the Effects of Chamomile (Matricaria Chamomilla L. ) and Cabergoline on Idiopathic Hyperprolactinemia: A Pilot Randomized Controlled Trial. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), 18(3), 1612-1621. SID. https://sid.ir/paper/289179/en

Vancouver: Copy

Kabiri Marya, KAMALINEJAD MOHAMMAD, BIOOS SOODABEH, SHARIAT MAMAK, SOHRABVAND FARNAZ. Comparative Study of the Effects of Chamomile (Matricaria Chamomilla L. ) and Cabergoline on Idiopathic Hyperprolactinemia: A Pilot Randomized Controlled Trial. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)[Internet]. 2019;18(3):1612-1621. Available from: https://sid.ir/paper/289179/en

IEEE: Copy

Marya Kabiri, MOHAMMAD KAMALINEJAD, SOODABEH BIOOS, MAMAK SHARIAT, and FARNAZ SOHRABVAND, “Comparative Study of the Effects of Chamomile (Matricaria Chamomilla L. ) and Cabergoline on Idiopathic Hyperprolactinemia: A Pilot Randomized Controlled Trial,” IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), vol. 18, no. 3, pp. 1612–1621, 2019, [Online]. Available: https://sid.ir/paper/289179/en

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