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Information Journal Paper

Title

GASTROINTESTINAL MANIFESTATIONS OF PATIENTS WITH CHRONIC GRANULOMATOUS DISEASE

Pages

  83-87

Abstract

 CHRONIC GRANULOMATOUS DISEASE (CGD) represents a group of inherited disorders of phagocytic system, manifesting recurrent INFECTIONs at different sites. The present study was accomplished in order to determine the gastrointestinal manifestations of CGD patients. Fifty-seven patients (38 males and 19 females) with CGD, who had been referred to three immunodeficiency referral centers in Iran, were studied during a 24-year period (1980-2004). The median age at the time of study was 14.5 years old (1-56 years). The median onset age of symptoms was 5 months (1 month – 13.75 years), and that of diagnostic age was 5 years (2 months- 54.1 years), with a diagnostic delay of 33 months, on average. Seven patients were presented with acute DIARRHEA, 3 with oral candidiasis, and 2 with liver abscesses as the first chief complaints. Twenty-four cases (42.1%) had been complicated by gastrointestinal manifestations during their course of the disease. Of those, 12 cases (21.1%) had DIARRHEA, 7 (12.3%) oral candidiasis, 5 (8.8%) hepatitis, 4 (7.0%) hepatic abscess, and 2 cases (3.5%) gastric outlet obstruction. Also, failure to thrive was detected in 6 patients (10.5%). Four patients died (7%). CGD should be excluded in any patient with gastrointestinal manifestations especially chronic DIARRHEA, hepatic abscess, and gastric outlet obstruction.

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    APA: Copy

    MOVAHEDI, M., AGHAMOHAMMADI, A., REZAEI, N., FARHOUDI, A., POURPAK, Z., MOEIN, M., GHARAGOZLOU, M., ATAROD, L., MIRSAEID GHAZI, B., SHAHNAVAZ, N., ABOLMAALI, K., MAHMOUDI, M., BAZARGAN, N., AHMADI AFSHAR, AKEFEH, NABAVI, M., BABAEI JANDAGHI, A., MANSOURI, DAVOUD, & ARSHI, S.. (2004). GASTROINTESTINAL MANIFESTATIONS OF PATIENTS WITH CHRONIC GRANULOMATOUS DISEASE. IRANIAN JOURNAL OF ALLERGY, ASTHMA AND IMMUNOLOGY (IJAAI), 3(2), 83-87. SID. https://sid.ir/paper/291061/en

    Vancouver: Copy

    MOVAHEDI M., AGHAMOHAMMADI A., REZAEI N., FARHOUDI A., POURPAK Z., MOEIN M., GHARAGOZLOU M., ATAROD L., MIRSAEID GHAZI B., SHAHNAVAZ N., ABOLMAALI K., MAHMOUDI M., BAZARGAN N., AHMADI AFSHAR AKEFEH, NABAVI M., BABAEI JANDAGHI A., MANSOURI DAVOUD, ARSHI S.. GASTROINTESTINAL MANIFESTATIONS OF PATIENTS WITH CHRONIC GRANULOMATOUS DISEASE. IRANIAN JOURNAL OF ALLERGY, ASTHMA AND IMMUNOLOGY (IJAAI)[Internet]. 2004;3(2):83-87. Available from: https://sid.ir/paper/291061/en

    IEEE: Copy

    M. MOVAHEDI, A. AGHAMOHAMMADI, N. REZAEI, A. FARHOUDI, Z. POURPAK, M. MOEIN, M. GHARAGOZLOU, L. ATAROD, B. MIRSAEID GHAZI, N. SHAHNAVAZ, K. ABOLMAALI, M. MAHMOUDI, N. BAZARGAN, AKEFEH AHMADI AFSHAR, M. NABAVI, A. BABAEI JANDAGHI, DAVOUD MANSOURI, and S. ARSHI, “GASTROINTESTINAL MANIFESTATIONS OF PATIENTS WITH CHRONIC GRANULOMATOUS DISEASE,” IRANIAN JOURNAL OF ALLERGY, ASTHMA AND IMMUNOLOGY (IJAAI), vol. 3, no. 2, pp. 83–87, 2004, [Online]. Available: https://sid.ir/paper/291061/en

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