RECURRENT INFECTIONS AND BILATERAL UVEITIS IN A PATIENT WITH CD8 DEFICIENCY

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

FARHOUDI A.; CHAVOSHZADEH Z.; MIRSAEID GHAZI B.; AGHAMOHAMMADI A.; GHARAGOZLOU M.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Journal of Allergy, Asthma and Immunology Year:2005 | Volume:4 | Issue:1 Page(s): 43-45

Download Full-Text

View:

342

Download:

124

Cites:

Information Journal Paper

Title

RECURRENT INFECTIONS AND BILATERAL UVEITIS IN A PATIENT WITH CD8 DEFICIENCY

Author(s)

Keywords

CD8-POSITIVE T-LYMPHOCYTES

IMMUNOLOGIC DEFICIENCY SYNDROMES

UVEITIS

ZAP 70 PROTEIN

Abstract

CD8 deficiency is a rare primary immunodeficiency with low or absent peripheral CD8 cells which results from TAP deficiency, Zap 70 deficiency and CD8 α gene mutation. We report a 14 year old female who presented with a history of recurrent pneumonia, bronchiectasis, otitis, severe varicella, herpetic lesions of mouth, bilateral UVEITIS, and cataract formation since the age of 8 years.She had growth failure, a huge spleen and moderate clubbing. In immunologic workup, humoral and phagocytic systems were normal. DTH response to candida, PPD and DT were negative but LTT response to PHA mitogen was normal. HLA typing showed normal class I expression. Flowcytometry of peripheral blood showed CD8: 0 to 2% (absolute count, 0-60 cells/mm3) with increased CD4/CD8 ratio on several occasions.Diagnosis of this patient cannot be HLA class I deficiency (TAP1 or TAP2), because class I expression had been normal. It is possible to be Zap -70 deficiency or CD8 α gene mutation. Bilateral UVEITIS in our patient was a unique presentation which might have resulted because of immune dysregulation in CID.

Cites

No record.

References

No record.

Cite

APA: Copy

FARHOUDI, A., CHAVOSHZADEH, Z., MIRSAEID GHAZI, B., AGHAMOHAMMADI, A., & GHARAGOZLOU, M.. (2005). RECURRENT INFECTIONS AND BILATERAL UVEITIS IN A PATIENT WITH CD8 DEFICIENCY. IRANIAN JOURNAL OF ALLERGY, ASTHMA AND IMMUNOLOGY (IJAAI), 4(1), 43-45. SID. https://sid.ir/paper/291081/en

Vancouver: Copy

FARHOUDI A., CHAVOSHZADEH Z., MIRSAEID GHAZI B., AGHAMOHAMMADI A., GHARAGOZLOU M.. RECURRENT INFECTIONS AND BILATERAL UVEITIS IN A PATIENT WITH CD8 DEFICIENCY. IRANIAN JOURNAL OF ALLERGY, ASTHMA AND IMMUNOLOGY (IJAAI)[Internet]. 2005;4(1):43-45. Available from: https://sid.ir/paper/291081/en

IEEE: Copy

A. FARHOUDI, Z. CHAVOSHZADEH, B. MIRSAEID GHAZI, A. AGHAMOHAMMADI, and M. GHARAGOZLOU, “RECURRENT INFECTIONS AND BILATERAL UVEITIS IN A PATIENT WITH CD8 DEFICIENCY,” IRANIAN JOURNAL OF ALLERGY, ASTHMA AND IMMUNOLOGY (IJAAI), vol. 4, no. 1, pp. 43–45, 2005, [Online]. Available: https://sid.ir/paper/291081/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops