SEROTONIN IN ALLERGIC RHINITIS: A POSSIBLE ROLE FOR BEHAVIOURAL SYMPTOMS

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CIPRANDI GIORGIO; DE AMICI MARA; TOSCA MARIANGELA; ALESINA ROBERTA; MARSEGLIA GIAN LUIGI; FUCHS DIETMAR

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Journal: Iranian Journal of Allergy, Asthma and Immunology Year:2011 | Volume:10 | Issue:3 Page(s): 183-188

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Title

SEROTONIN IN ALLERGIC RHINITIS: A POSSIBLE ROLE FOR BEHAVIOURAL SYMPTOMS

Author(s)

Keywords

ALLERGIC RHINITIS

BEHAVIORAL SYMPTOMS

POLLEN ALLERGEN EXPOSURE

SERUM

SEROTONIN

Abstract

ALLERGIC RHINITIS (AR) is a very frequent disease which is not only characterized by nasal symptoms, but also with behavioural changes. This study evaluated the SERUM SEROTONIN levels in patients with pollen-induced AR during and outside the pollen season.One-hundred-two (56 females, 46 males, median age: 28.7 years) were included in this study: 56 with seasonal AR (SAR) evaluated outside the pollen season and so without allergic inflammation and symptoms, and 46 with SAR evaluated during the pollen season with symptoms. Blood specimens were collected to assess SERUM concentrations of SEROTONIN and to compare results to scores of a Quality of Life (QoL) questionnaire which was performed in all subjects.Serotonin SERUM concentrations were higher in AR patients out of pollen season than in (p<0.01). There was a very strong direct relationship between QoL and SEROTONIN concentrations.This preliminary study demonstrates that SAR influences SEROTONIN concentrations and that SERUM SEROTONIN could serve as a biomarker in AR patients with behavioural symptoms.

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APA: Copy

CIPRANDI, GIORGIO, DE AMICI, MARA, TOSCA, MARIANGELA, ALESINA, ROBERTA, MARSEGLIA, GIAN LUIGI, & FUCHS, DIETMAR. (2011). SEROTONIN IN ALLERGIC RHINITIS: A POSSIBLE ROLE FOR BEHAVIOURAL SYMPTOMS. IRANIAN JOURNAL OF ALLERGY, ASTHMA AND IMMUNOLOGY (IJAAI), 10(3), 183-188. SID. https://sid.ir/paper/291285/en

Vancouver: Copy

CIPRANDI GIORGIO, DE AMICI MARA, TOSCA MARIANGELA, ALESINA ROBERTA, MARSEGLIA GIAN LUIGI, FUCHS DIETMAR. SEROTONIN IN ALLERGIC RHINITIS: A POSSIBLE ROLE FOR BEHAVIOURAL SYMPTOMS. IRANIAN JOURNAL OF ALLERGY, ASTHMA AND IMMUNOLOGY (IJAAI)[Internet]. 2011;10(3):183-188. Available from: https://sid.ir/paper/291285/en

IEEE: Copy

GIORGIO CIPRANDI, MARA DE AMICI, MARIANGELA TOSCA, ROBERTA ALESINA, GIAN LUIGI MARSEGLIA, and DIETMAR FUCHS, “SEROTONIN IN ALLERGIC RHINITIS: A POSSIBLE ROLE FOR BEHAVIOURAL SYMPTOMS,” IRANIAN JOURNAL OF ALLERGY, ASTHMA AND IMMUNOLOGY (IJAAI), vol. 10, no. 3, pp. 183–188, 2011, [Online]. Available: https://sid.ir/paper/291285/en

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