THE ROLE OF RHEUMATOID FACTOR AND ANTI-CYCLIC CITRULLINATED PEPTIDE ANTIBODY IN DIAGNOSIS OF RHEUMATOID ARTHRITIS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MOBINI MARYAM; KASHI Z.; MAHDAVI M.R.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Red Crescent Medical Journal Year:2010 | Volume:12 | Issue:2 Page(s): 100-103

Download Full-Text

View:

444

Download:

261

Cites:

Information Journal Paper

Title

THE ROLE OF RHEUMATOID FACTOR AND ANTI-CYCLIC CITRULLINATED PEPTIDE ANTIBODY IN DIAGNOSIS OF RHEUMATOID ARTHRITIS

Author(s)

MOBINI MARYAM | KASHI Z. | MAHDAVI M.R. | Issue Writer Certificate

Keywords

ANTI-CCP

RHEUMATOID ARTHRITIS

RHEUMATOID FACTOR

Abstract

Background: RHEUMATOID FACTOR (RF) occurs in 70-90% of patients with established RHEUMATOID ARTHRITIS (RA). Anti-cyclic citrullinated peptide antibody (ANTI-CCP) detection may be used to confirm the diagnosis of RA in patients with uncharacterized chronic inflammatory arthritis. This study is an attempt to evaluate the role of RF and ANTI-CCP in the diagnosis and prognosis of RHEUMATOID ARTHRITIS.Methods: Blood samples were obtained from 55 patients with established RA and 55 healthy controls. ANTI-CCP and RF were measured by ELISA and nephelometry. The patient's demographics, disease duration, DMARDs usage, ESR and radiographic abnormalities were recorded.Results: Fifty five RA patients and 55 healthy age and sex matched controls were enrolled. Odd ratio (OR) was 87.42 (CI=11.2-680.1) for RF and 27.48 (6/08-124/09) for Anti- CCP. Five patients had used more than 3 DMARDs; all of them were RF positive and 4 were also ANTI-CCP positive. Eleven patients had erosions in their radiographs; 10 of them were seropositive for RF and 9 positive for ANTI-CCP.Conclusion: Our study suggests that despite lack of specificity, RF continues to be a central part of the definition of RA due to favorable sensitivity profile and the combined use of RF. Also, ANTI-CCP is a more powerful diagnostic and prognostic tool.

Cites

No record.

References

No record.

Cite

APA: Copy

MOBINI, MARYAM, KASHI, Z., & MAHDAVI, M.R.. (2010). THE ROLE OF RHEUMATOID FACTOR AND ANTI-CYCLIC CITRULLINATED PEPTIDE ANTIBODY IN DIAGNOSIS OF RHEUMATOID ARTHRITIS. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), 12(2), 100-103. SID. https://sid.ir/paper/292241/en

Vancouver: Copy

MOBINI MARYAM, KASHI Z., MAHDAVI M.R.. THE ROLE OF RHEUMATOID FACTOR AND ANTI-CYCLIC CITRULLINATED PEPTIDE ANTIBODY IN DIAGNOSIS OF RHEUMATOID ARTHRITIS. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ)[Internet]. 2010;12(2):100-103. Available from: https://sid.ir/paper/292241/en

IEEE: Copy

MARYAM MOBINI, Z. KASHI, and M.R. MAHDAVI, “THE ROLE OF RHEUMATOID FACTOR AND ANTI-CYCLIC CITRULLINATED PEPTIDE ANTIBODY IN DIAGNOSIS OF RHEUMATOID ARTHRITIS,” IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), vol. 12, no. 2, pp. 100–103, 2010, [Online]. Available: https://sid.ir/paper/292241/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops