BONE LOSS WITH MULTIPLE SCLEROSIS: EFFECT OF GLUCOCORTICOID USE AND FUNCTIONAL STATUS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

DABBAGHMANESH M.H.; YOUSEFIPOUR GH.A.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Red Crescent Medical Journal Year:2011 | Volume:13 | Issue:1 Page(s): 9-14

Download Full-Text

View:

292

Download:

105

Cites:

Information Journal Paper

Title

BONE LOSS WITH MULTIPLE SCLEROSIS: EFFECT OF GLUCOCORTICOID USE AND FUNCTIONAL STATUS

Author(s)

DABBAGHMANESH M.H. | YOUSEFIPOUR GH.A. | Issue Writer Certificate

Keywords

MULTIPLE SCLEROSIS

BONE MINERAL DENSITY

AMBULATION

STEROID

Abstract

Background: Emerging data suggest a significantly increased prevalence of low BONE MINERAL DENSITY (BMD) in men and women with MULTIPLE SCLEROSIS (MS) compared to age matched controls. This study was performed to evaluate bone mineral mass in patients with MS in comparison to healthy age-and sex matched controls and to determine association of glucocorticoid use or AMBULATION ability with changing in bone mass in these individuals.Methods: Eighty two patients with MS and 328 age-sex matched healthy controls participated in the study. The Kurtzke expanded disability status scale (EDSS) was used to evaluate disability and functional capacity. BONE MINERAL DENSITY was measured using Dual X-ray absorptiometry. Serum calcium, phosphorus and 25 (OH) vitamin D levels were assessed.Results: The MS patients had significantly lower BMD at the lumbar spines, neck and total femur compared to age-sex matched controls. EDSS scores were inversely correlated with total femur and spinal BMD. There was a negative correlation with cumulative STEROID dose and BMD only for femoral neck.Conclusion: BMD was significantly lower in MS patients. Decreased ambulatory status and glucocorticoid usage were associated with low BMD in MS patients. These patients should be encouraged to increase mobility and to have protective measures to maintain bone mass.

Cites

No record.

References

No record.

Cite

APA: Copy

DABBAGHMANESH, M.H., & YOUSEFIPOUR, GH.A.. (2011). BONE LOSS WITH MULTIPLE SCLEROSIS: EFFECT OF GLUCOCORTICOID USE AND FUNCTIONAL STATUS. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), 13(1), 9-14. SID. https://sid.ir/paper/292317/en

Vancouver: Copy

DABBAGHMANESH M.H., YOUSEFIPOUR GH.A.. BONE LOSS WITH MULTIPLE SCLEROSIS: EFFECT OF GLUCOCORTICOID USE AND FUNCTIONAL STATUS. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ)[Internet]. 2011;13(1):9-14. Available from: https://sid.ir/paper/292317/en

IEEE: Copy

M.H. DABBAGHMANESH, and GH.A. YOUSEFIPOUR, “BONE LOSS WITH MULTIPLE SCLEROSIS: EFFECT OF GLUCOCORTICOID USE AND FUNCTIONAL STATUS,” IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), vol. 13, no. 1, pp. 9–14, 2011, [Online]. Available: https://sid.ir/paper/292317/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops