ANTIBIOTIC SUSCEPTIBILITY PATTERNS AND MOLECULAR EPIDEMIOLOGY OF METALLO-β-LACTAMASE PRODUCING PSEUDOMONAS AERUGINOSA STRAINS ISOLATED FROM BURN PATIENTS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

JAPONI AZIZ; ANVARINEJAD MOJTABA; FARSHAD SHOHREH; GIAMMANCO GIOVANNI M.; RAFAATPOUR NORODDIN; ALIPOUR EBRAHIM

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Red Crescent Medical Journal Year:2014 | Volume:16 | Issue:5 Page(s): 1-6

Download Full-Text

View:

338

Download:

152

Cites:

Information Journal Paper

Title

ANTIBIOTIC SUSCEPTIBILITY PATTERNS AND MOLECULAR EPIDEMIOLOGY OF METALLO-β-LACTAMASE PRODUCING PSEUDOMONAS AERUGINOSA STRAINS ISOLATED FROM BURN PATIENTS

Author(s)

Keywords

BETA-LACTAMASES

IMIPENEM

MEROPENEM

PULSED FIELD GEL ELECTROPHORESI

Abstract

Background: Failure in the treatment of burn patients infected with Pseudomonas aeruginosa could happen as a result of the acquisition of antibiotic resistance, including carbapenems.Objectives: The aim of the present study was to investigate the phenotypic and genotypic characteristics of the Pseudomonas aeruginosa strains, isolated from burn patients.Patients and Methods: During a 12 month period, in this cross-sectional study, two hundred seventy strains of Pseudomonas aeruginosa were isolated from the burn patients in Ghotbeddin Burn Hospital, Shiraz, Iran. Screening for the carbapenem resistance in the isolates was carried out by the E test method. Sensitivity patterns of metallo-b-lactamase (MbLs) producing strains of pseudomonas to eleven antibiotics were determined by the mentioned method. The epidemiological associations of these strains were determined by Pulsed-field gel electrophoresis (PFGE).Results: Of the 270 strains, 60 (22.2%) were resistant to IMIPENEM and MEROPENEM, classified as MbLs producing. MbLs producing strains of pseudomonas were completely resistant to five tested antibiotics while their sensitivities to the three most effective antibiotics including ceftazidime, amikacin and ciprofloxacin were 23.4%, 6.7 % and 1.7%, respectively. In PFGE, 37 patterns from the genome of Pseudomonas aeruginosa were observed. Majority of the strains (43, 71.6%) exhibited more than 80% similarity, based on the drawn dendrogram.Conclusions: According to the results, none of the tested antibiotics is safe to prescribe. As PFGE revealed, a limited number of Pseudomonas aeruginosa types are predominant in the hospitals which infect the burn patients.

Cites

References

No record.

Cite

APA: Copy

JAPONI, AZIZ, ANVARINEJAD, MOJTABA, FARSHAD, SHOHREH, GIAMMANCO, GIOVANNI M., RAFAATPOUR, NORODDIN, & ALIPOUR, EBRAHIM. (2014). ANTIBIOTIC SUSCEPTIBILITY PATTERNS AND MOLECULAR EPIDEMIOLOGY OF METALLO-β-LACTAMASE PRODUCING PSEUDOMONAS AERUGINOSA STRAINS ISOLATED FROM BURN PATIENTS. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), 16(5), 1-6. SID. https://sid.ir/paper/292594/en

Vancouver: Copy

JAPONI AZIZ, ANVARINEJAD MOJTABA, FARSHAD SHOHREH, GIAMMANCO GIOVANNI M., RAFAATPOUR NORODDIN, ALIPOUR EBRAHIM. ANTIBIOTIC SUSCEPTIBILITY PATTERNS AND MOLECULAR EPIDEMIOLOGY OF METALLO-β-LACTAMASE PRODUCING PSEUDOMONAS AERUGINOSA STRAINS ISOLATED FROM BURN PATIENTS. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ)[Internet]. 2014;16(5):1-6. Available from: https://sid.ir/paper/292594/en

IEEE: Copy

AZIZ JAPONI, MOJTABA ANVARINEJAD, SHOHREH FARSHAD, GIOVANNI M. GIAMMANCO, NORODDIN RAFAATPOUR, and EBRAHIM ALIPOUR, “ANTIBIOTIC SUSCEPTIBILITY PATTERNS AND MOLECULAR EPIDEMIOLOGY OF METALLO-β-LACTAMASE PRODUCING PSEUDOMONAS AERUGINOSA STRAINS ISOLATED FROM BURN PATIENTS,” IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), vol. 16, no. 5, pp. 1–6, 2014, [Online]. Available: https://sid.ir/paper/292594/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops