مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

EVALUATION OF ORAL GINGER EFFICACY AGAINST POSTOPERATIVE NAUSEA AND VOMITING: A RANDOMIZED DOUBLE-BLINDED CLINICAL TRIAL

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Abstract

 Background: Postoperative NAUSEA and VOMITING is one of the most common side effects associated with surgical procedures.Objectives: The aim of this study was to determine the effect of GINGER on intensity of NAUSEA and VOMITING after surgical procedures.Patients and Methods: This study was a randomized, double blinded, clinical trial. 160 eligible patients were randomly assigned into experimental or placebo groups. The experimental group received 4 capsules containing 250 mg GINGER and placebo group received 4 placebo capsules 1 hour before surgery. The severity of NAUSEA and VOMITING was measured at 2, 4, 6 hours post operation using visual analogue scale and a structured questionnaire. The data were analyzed by independent t-test, Mann-Whitney U test, chi-square and GEE using SPSS 16 and STATA version 11.Results: Mean NAUSEA score at 2 hours post operation was significantly lower in the experimental group (P=0.04). Mean NAUSEA score at 4 and 6 hours post operation was lower in the experimental group; however, there was no significant difference between the groups at any time post operation. The frequencies of NAUSEA in the experimental group at 2 and 6 hours post operation were lower than that in the placebo group, however, at 2 hours post operation, it was borderline significant (P=0.05) There was no significant differences between two group in the intensity of VOMITING at any time.Conclusions: Use of GINGER was effective at decreasing postoperative NAUSEA. GINGER could be used as a safe antiemetic drug at post operation.

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    APA: Copy

    MONTAZERI, AKRAMSADAT, HAMIDZADEH, AZAM, RAEI, MEHDI, MOHAMMADIUN, MALIHE, MONTAZERI, AZAM SADAT, MIRSHAHI, REZA, & ROHANI, HOSEIN. (2013). EVALUATION OF ORAL GINGER EFFICACY AGAINST POSTOPERATIVE NAUSEA AND VOMITING: A RANDOMIZED DOUBLE-BLINDED CLINICAL TRIAL. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), 15(12), 0-0. SID. https://sid.ir/paper/292778/en

    Vancouver: Copy

    MONTAZERI AKRAMSADAT, HAMIDZADEH AZAM, RAEI MEHDI, MOHAMMADIUN MALIHE, MONTAZERI AZAM SADAT, MIRSHAHI REZA, ROHANI HOSEIN. EVALUATION OF ORAL GINGER EFFICACY AGAINST POSTOPERATIVE NAUSEA AND VOMITING: A RANDOMIZED DOUBLE-BLINDED CLINICAL TRIAL. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ)[Internet]. 2013;15(12):0-0. Available from: https://sid.ir/paper/292778/en

    IEEE: Copy

    AKRAMSADAT MONTAZERI, AZAM HAMIDZADEH, MEHDI RAEI, MALIHE MOHAMMADIUN, AZAM SADAT MONTAZERI, REZA MIRSHAHI, and HOSEIN ROHANI, “EVALUATION OF ORAL GINGER EFFICACY AGAINST POSTOPERATIVE NAUSEA AND VOMITING: A RANDOMIZED DOUBLE-BLINDED CLINICAL TRIAL,” IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), vol. 15, no. 12, pp. 0–0, 2013, [Online]. Available: https://sid.ir/paper/292778/en

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