ALPHA-1 ANTITRYPSIN DEFICIENCY IN IRANIAN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE

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GERAMIZADEH BITA; JOWKAR ZAHRA; KARAMI LEILA; MASOUMPOUR MASOUM; MEHRABI SAMRAD; GHAYOUMI MOHAMMAD ALI

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Journal Paper

Paper Information

Journal: Iranian Red Crescent Medical Journal Year:2013 | Volume:15 | Issue:11 Page(s): 0-0

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Title

ALPHA-1 ANTITRYPSIN DEFICIENCY IN IRANIAN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE

Author(s)

Keywords

ALPHA-1 ANTITRYPSIN DEFICIENCY

COPD

IRAN

Abstract

Background: ALPHA-1 ANTITRYPSIN DEFICIENCY is a genetic disease which affects both lung and liver. This disease is a recognized factor for chronic obstructive pulmonary disease (COPD). However its importance as the cause of COPD in a country such as IRAN is unclear.Objectives: This study was conducted to find out the role of α-1 antitrypsin deficiency as a cause of COPD in IRANian patients.Materials and Methods: The serum concentration of α-1 antitrypsin was determined and the genotype of a-1 antitrypsin was also evaluated by PCR-RFLP in 130 patients with COPD and 50 normal healthy blood donors.Results: No α-1 antitrypsin deficient case was found in normal healthy people and COPD patients.Conclusions: Our results clarify that deficiency of α-antitrypsin is not a major cause of COPD in IRANian patients.

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APA: Copy

GERAMIZADEH, BITA, JOWKAR, ZAHRA, KARAMI, LEILA, MASOUMPOUR, MASOUM, MEHRABI, SAMRAD, & GHAYOUMI, MOHAMMAD ALI. (2013). ALPHA-1 ANTITRYPSIN DEFICIENCY IN IRANIAN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), 15(11), 0-0. SID. https://sid.ir/paper/292791/en

Vancouver: Copy

GERAMIZADEH BITA, JOWKAR ZAHRA, KARAMI LEILA, MASOUMPOUR MASOUM, MEHRABI SAMRAD, GHAYOUMI MOHAMMAD ALI. ALPHA-1 ANTITRYPSIN DEFICIENCY IN IRANIAN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ)[Internet]. 2013;15(11):0-0. Available from: https://sid.ir/paper/292791/en

IEEE: Copy

BITA GERAMIZADEH, ZAHRA JOWKAR, LEILA KARAMI, MASOUM MASOUMPOUR, SAMRAD MEHRABI, and MOHAMMAD ALI GHAYOUMI, “ALPHA-1 ANTITRYPSIN DEFICIENCY IN IRANIAN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE,” IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), vol. 15, no. 11, pp. 0–0, 2013, [Online]. Available: https://sid.ir/paper/292791/en

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