TRANSCRANIAL DOPPLER ULTRASONOGRAPHY IN BETA-THALASSEMIA MAJOR PATIENTS WITHOUT AND WITH THROMBOCYTOSIS

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SHARIAT ABDOLHAMID; NAZERI MASOUME; ABOLHASANI FOROUGHI AMIN; KARIMI MEHRAN

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Journal Paper

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Journal: Iranian Red Crescent Medical Journal Year:2013 | Volume:15 | Issue:3 Page(s): 234-238

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Title

TRANSCRANIAL DOPPLER ULTRASONOGRAPHY IN BETA-THALASSEMIA MAJOR PATIENTS WITHOUT AND WITH THROMBOCYTOSIS

Author(s)

SHARIAT ABDOLHAMID | NAZERI MASOUME | ABOLHASANI FOROUGHI AMIN | KARIMI MEHRAN | Issue Writer Certificate

Keywords

BETA-THALASSEMIA

THROMBOCYTOSIS

ULTRASONOGRAPHY

DOPPLER

TRANSCRANIAL

Abstract

Background: BETA-THALASSEMIA is a type of anemia in which the patients may require splenectomy and this can lead to THROMBOCYTOSIS with increased risk of stroke. TRANSCRANIAL DOPPLER ultrasound is a method for determining cerebral vessel stenosis.Objectives: The aim of this study was to investigate whether the risk of a future stroke secondary to cerebral artery stenosis can be predicted with the use of TRANSCRANIAL DOPPLER ultrasound in BETA-THALASSEMIA major patients.Patients and Methods: This study included 54 BETA-THALASSEMIA major patients divided into 2 groups; group A consisted of 28 patients who have THROMBOCYTOSIS secondary to a previous splenectomy and group B comprised of 26 patients who did not have a splenectomy with normal platelet count, as well as a control group of 30 healthy individuals.Results: TRANSCRANIAL DOPPLER ultrasound of the cerebral vessels were performed in all participants, and the results for each group were compared with the controls. In addition, patients were evaluated for evidence of high flow velocity in the cerebral vessels that met the clinically significant criteria of³50% stenosis. TRANSCRANIAL DOPPLER ultrasound velocity criteria for dgt; 50% stenosis, indicating a risk of stroke, were not documented in any patients but increase in cerebral blood velocities in many arteries in group A and in some arteries in group B were revealed.Conclusion: Following splenectomy, THROMBOCYTOSIS can predispose the patients to an increase in cerebral blood velocities more than respected with anemia. But by TRANSCRANIAL DOPPLER ULTRASONOGRAPHY no evidence of significant stenosis were found in intracerebral arteries to conclude that the BETA-THALASSEMIA major patients were more prone to the development of stroke secondary to this abnormality.

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APA: Copy

SHARIAT, ABDOLHAMID, NAZERI, MASOUME, ABOLHASANI FOROUGHI, AMIN, & KARIMI, MEHRAN. (2013). TRANSCRANIAL DOPPLER ULTRASONOGRAPHY IN BETA-THALASSEMIA MAJOR PATIENTS WITHOUT AND WITH THROMBOCYTOSIS. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), 15(3), 234-238. SID. https://sid.ir/paper/292840/en

Vancouver: Copy

SHARIAT ABDOLHAMID, NAZERI MASOUME, ABOLHASANI FOROUGHI AMIN, KARIMI MEHRAN. TRANSCRANIAL DOPPLER ULTRASONOGRAPHY IN BETA-THALASSEMIA MAJOR PATIENTS WITHOUT AND WITH THROMBOCYTOSIS. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ)[Internet]. 2013;15(3):234-238. Available from: https://sid.ir/paper/292840/en

IEEE: Copy

ABDOLHAMID SHARIAT, MASOUME NAZERI, AMIN ABOLHASANI FOROUGHI, and MEHRAN KARIMI, “TRANSCRANIAL DOPPLER ULTRASONOGRAPHY IN BETA-THALASSEMIA MAJOR PATIENTS WITHOUT AND WITH THROMBOCYTOSIS,” IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), vol. 15, no. 3, pp. 234–238, 2013, [Online]. Available: https://sid.ir/paper/292840/en

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