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Information Journal Paper

Title

PREDICTING OUTCOMES IN TRAUMATIC BRAIN INJURY USING THE GLASGOW COMA SCALE: A JOINT MODELING OF LONGITUDINAL MEASUREMENTS AND TIME TO EVENT

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Abstract

 Background: Traumatic brain injury (TBI) is an important public health problem throughout the world.Objectives: The aim of this study was to assess repeated GLASGOW COMA SCALE (GCS) scores in predicting the severity of TBI and patients’ survival.Patients and Methods: In this longitudinal study used a total sample of 239 patients, all of whom were hospitalized with traumatic BRAIN INJURIES. Subjects were selected by simple random sampling in intensive care unit (ICU) wards of the Shahid Beheshti hospital in Kashan, Iran between September 2008 and September 2010. The patients’ level of consciousness was evaluated using GCS at admission, six hours after admission to the ICU, and at the time of discharge from the hospital. A Glasgow outcome score (GOS) is used to classify the global outcomes in TBI survivors. A joint modeling approach was utilized for data analysis using R software.Results: The results showed that female patients had the risk of occurrence, slightly more than men, but this was not significant (HR=1.095 P=0.757). The mortality risk was significantly higher in older patients (HR=1.010, P=0.010). In addition, the results indicated a significant increasing linear trend in GCS values over time (HR=1.78, P=0.003). Higher age was also associated with lower GCS values over time (P<0.001). The severity of TBI decreases with increasing GCS values (P<0.001).Conclusions: By jointly modeling longitudinal data with time-to-event outcomes, our findings supported the use of the GCS scores in predicting the severity of TBI.

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    APA: Copy

    GILANI, NEDA, KAZEMNEJAD, ANOSHIRVAN, ZAYERI, FARID, ASGHARI JAFARABADI, MOHAMMAD, & IZADI AVANJI, FATEMEH SADAT. (2017). PREDICTING OUTCOMES IN TRAUMATIC BRAIN INJURY USING THE GLASGOW COMA SCALE: A JOINT MODELING OF LONGITUDINAL MEASUREMENTS AND TIME TO EVENT. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), 19(2), 0-0. SID. https://sid.ir/paper/293345/en

    Vancouver: Copy

    GILANI NEDA, KAZEMNEJAD ANOSHIRVAN, ZAYERI FARID, ASGHARI JAFARABADI MOHAMMAD, IZADI AVANJI FATEMEH SADAT. PREDICTING OUTCOMES IN TRAUMATIC BRAIN INJURY USING THE GLASGOW COMA SCALE: A JOINT MODELING OF LONGITUDINAL MEASUREMENTS AND TIME TO EVENT. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ)[Internet]. 2017;19(2):0-0. Available from: https://sid.ir/paper/293345/en

    IEEE: Copy

    NEDA GILANI, ANOSHIRVAN KAZEMNEJAD, FARID ZAYERI, MOHAMMAD ASGHARI JAFARABADI, and FATEMEH SADAT IZADI AVANJI, “PREDICTING OUTCOMES IN TRAUMATIC BRAIN INJURY USING THE GLASGOW COMA SCALE: A JOINT MODELING OF LONGITUDINAL MEASUREMENTS AND TIME TO EVENT,” IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), vol. 19, no. 2, pp. 0–0, 2017, [Online]. Available: https://sid.ir/paper/293345/en

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