CLINICAL SIGNIFICANCE OF ABNORMAL RESULTS OF SECOND TRIMESTERHORMONES IN THE ABSENCE OF ANEUPLOIDY

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

UZUN ISIL; SAYIN N CENK; INAN CIHAN; ERZINCAN SELEN; SUTCU HAVVA; VAROL FUSUN

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Red Crescent Medical Journal Year:2018 | Volume:20 | Issue:4 Page(s): 0-0

Download Full-Text

View:

194

Download:

111

Cites:

Information Journal Paper

Title

CLINICAL SIGNIFICANCE OF ABNORMAL RESULTS OF SECOND TRIMESTERHORMONES IN THE ABSENCE OF ANEUPLOIDY

Author(s)

Keywords

ANEUPLOIDY

DISORDERS

GENETIC

HORMONE

PREECLAMPSIA

PREGNANCY

Abstract

Background: Abnormal levels of HORMONEs during the second trimester of PREGNANCY may predict GENETIC DISORDERS and complicationsof PREGNANCY. Objectives: This study was performed to evaluate the clinical significance of abnormal results in second-trimester markers in theabsence of ANEUPLOIDY. Methods: This case-control study was conducted between May 2014 and December 2015 in the maternal-fetal unit, Trakya UniversityFaculty of Medicine in Turkey. Overall, 108 Turkish pregnant females were included in this study. This research recruited patients(n = 46) with normal karyotype, who underwent invasive prenatal tests because of abnormal levels of second-trimester HORMONEs, along with a cohort of controls (n = 31) with hormonal results within normal ranges. For each patient, the researchers recordedthe mode of delivery, gestational age at delivery, birth weight, complications, and adverse outcome of the PREGNANCY. Data wereanalyzed using Fisher’ s exact tests and Yates continuity correction tests for qualitative variables, and t-test and Mann-Whitney Utest for quantitative variables. Results: Maternal age (mean SD) of the entire group was 31. 77 5. 68 years (study group: 31. 23 4. 39; controls: 32. 13 6. 43, P >0. 05). Preterm delivery and PREECLAMPSIA were significantly higher in the study group (P = 0. 02). In the study group, Alpha Fetoprotein(AFP) levels were significantly higher in patients with PREECLAMPSIA yet not in the controls. The AFP values under 0. 77 multipleof the median in patients with elevated test results in the absence of ANEUPLOIDY appeared to be associated with the developmentof PREECLAMPSIA later in PREGNANCY. Conclusions: Although the significance of higher AFP values have been discussed in the literature in terms of the development ofadverse outcomes, the present study suggests that lower values must also be taken into account during patient follow-up.

Cites

No record.

References

First-Trimester and Second-Trimester Maternal Serum Biomarkers as Predictors of Placental Abruption

Cite

APA: Copy

UZUN, ISIL, SAYIN, N CENK, INAN, CIHAN, ERZINCAN, SELEN, SUTCU, HAVVA, & VAROL, FUSUN. (2018). CLINICAL SIGNIFICANCE OF ABNORMAL RESULTS OF SECOND TRIMESTERHORMONES IN THE ABSENCE OF ANEUPLOIDY. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), 20(4), 0-0. SID. https://sid.ir/paper/293718/en

Vancouver: Copy

UZUN ISIL, SAYIN N CENK, INAN CIHAN, ERZINCAN SELEN, SUTCU HAVVA, VAROL FUSUN. CLINICAL SIGNIFICANCE OF ABNORMAL RESULTS OF SECOND TRIMESTERHORMONES IN THE ABSENCE OF ANEUPLOIDY. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ)[Internet]. 2018;20(4):0-0. Available from: https://sid.ir/paper/293718/en

IEEE: Copy

ISIL UZUN, N CENK SAYIN, CIHAN INAN, SELEN ERZINCAN, HAVVA SUTCU, and FUSUN VAROL, “CLINICAL SIGNIFICANCE OF ABNORMAL RESULTS OF SECOND TRIMESTERHORMONES IN THE ABSENCE OF ANEUPLOIDY,” IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), vol. 20, no. 4, pp. 0–0, 2018, [Online]. Available: https://sid.ir/paper/293718/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops