مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Title

COMPARING THE EFFECT OF LIDOCAINE, MAGNESIUM SULFATE COMBINATIONWITH AMIODARONE, MAGNESIUM SULFATE COMBINATION IN PREVENTINGVENTRICULAR FIBRILLATION AFTER AORTIC ARTERY CROSS, CLAMP REMOVALDURING CORONARY ARTERY BYPASS GRAFT SURGERY

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Abstract

 Background: The prevalence of VENTRICULAR FIBRILLATION after removal of the aortic cross-clamp in patients undergoing coronaryartery BYPASS surgery is about 74%-96%. Defibrillation shock and different types of agents are used to treat VENTRICULAR FIBRILLATION(VF). Objectives: This study was aimed to compare the effects of combining LIDOCAINE + MAGNESIUM SULFATE with AMIODARONE + MagnesiumSulfate in the prevention of reperfusion-induced VENTRICULAR FIBRILLATION. Methods: This randomized, double-blinded clinical study included 74 ASA class II and III patients undergoing CORONARY ARTERY BYPASSgrafting (CABG) in a university-affiliated hospital, Bandar Abbas, Iran, in the years 2015-2016. Patients were divided into twogroups based on a random sample table of the lock. Both groups received MAGNESIUM SULFATE through the cardiopulmonary BYPASSpump. LIDOCAINE 2% (100 mg) and AMIODARONE (300 mg) were injected respectively to group LIDOCAINE + MAGNESIUM SULFATE (LM)and group AMIODARONE + MAGNESIUM SULFATE (AM) patients before aortic cross-clamp release. The incidences of arrhythmias wererecorded within 30 minutes after release of the aortic cross-clamp (ACC). Additionally, the defibrillation shocks (frequency andlevel of Joules delivered), amount of inotrope agent, and the hemodynamic and arterial blood gas parameters were recorded up to24 hours postoperatively. Results: There was no significant difference between the two groups in terms of demographic characteristics, ejection fraction, andASA class. The prevalence of VENTRICULAR FIBRILLATION (VF) and ATRIAL FIBRILLATION (Af) 30 minutes after ACC release were 46. 7% and 53. 3%(P = 0. 240) vs. 33. 3% and 66. 7% (P > 0. 999); while, up to 24 hours post-operatively were 60% and 20. 0% vs. 0. 0% and 0. 0% in groupsLM and AM respectively. The number of defibrillations in the LIDOCAINE + MAGNESIUM SULFATE group was significantly higher; 57. 9%vs. 25% in groups LM and AM respectively (P = 0. 004). Conclusions: The use of AMIODARONE + MAGNESIUM SULFATE reduces the number of defibrillation following the release of the Aorticcross-clamp compared with LIDOCAINE + MAGNESIUM SULFATE.

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    APA: Copy

    KASHANI, SAEED, JARINESHIN, HASHEM, FEKRAT, FEREYDOON, MORADI SHAHDADI, MARYAM, & SOLTANI SHAHABADI, NEDA. (2018). COMPARING THE EFFECT OF LIDOCAINE, MAGNESIUM SULFATE COMBINATIONWITH AMIODARONE, MAGNESIUM SULFATE COMBINATION IN PREVENTINGVENTRICULAR FIBRILLATION AFTER AORTIC ARTERY CROSS, CLAMP REMOVALDURING CORONARY ARTERY BYPASS GRAFT SURGERY. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), 20(5), 0-0. SID. https://sid.ir/paper/293752/en

    Vancouver: Copy

    KASHANI SAEED, JARINESHIN HASHEM, FEKRAT FEREYDOON, MORADI SHAHDADI MARYAM, SOLTANI SHAHABADI NEDA. COMPARING THE EFFECT OF LIDOCAINE, MAGNESIUM SULFATE COMBINATIONWITH AMIODARONE, MAGNESIUM SULFATE COMBINATION IN PREVENTINGVENTRICULAR FIBRILLATION AFTER AORTIC ARTERY CROSS, CLAMP REMOVALDURING CORONARY ARTERY BYPASS GRAFT SURGERY. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ)[Internet]. 2018;20(5):0-0. Available from: https://sid.ir/paper/293752/en

    IEEE: Copy

    SAEED KASHANI, HASHEM JARINESHIN, FEREYDOON FEKRAT, MARYAM MORADI SHAHDADI, and NEDA SOLTANI SHAHABADI, “COMPARING THE EFFECT OF LIDOCAINE, MAGNESIUM SULFATE COMBINATIONWITH AMIODARONE, MAGNESIUM SULFATE COMBINATION IN PREVENTINGVENTRICULAR FIBRILLATION AFTER AORTIC ARTERY CROSS, CLAMP REMOVALDURING CORONARY ARTERY BYPASS GRAFT SURGERY,” IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), vol. 20, no. 5, pp. 0–0, 2018, [Online]. Available: https://sid.ir/paper/293752/en

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