EFFECT OF “ PISTACIA ATLANTICA” RESIN (BANEH) ON FUNCTIONAL DYSPEPSIA: ADOUBLE-BLIND, RANDOMIZED CLINICAL STUDY

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EFTEKHARAFZALI MAHDIYEHSADAT; MEHRABANI MITRA; TAJADINI HALEH; AHMADI BIJAN; ZAHEDI MOHAMMAD JAVAD

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Journal: Iranian Red Crescent Medical Journal Year:2018 | Volume:20 | Issue:7 Page(s): 0-0

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Title

EFFECT OF “ PISTACIA ATLANTICA” RESIN (BANEH) ON FUNCTIONAL DYSPEPSIA: ADOUBLE-BLIND, RANDOMIZED CLINICAL STUDY

Author(s)

Keywords

DYSPEPSIA

MEDICINAL

MEDICINE

PISTACIA

PLANT

TRADITIONAL

Abstract

Background: Functional DYSPEPSIA (FD) is one of the most common problems around the world. PISTACIA atlantica has beneficialeffects in gastrointestinal disorders and is used for treating functional DYSPEPSIA in Persian MEDICINE. Objectives: The aim of this study was to assess the effect of “ PISTACIA atlantica” (Baneh) on functional DYSPEPSIA. Methods: This randomized, double-blind, placebo-controlled trial was carried out on 119 patients (18 to 60 years old) with functionalDYSPEPSIA based on Rome III criteria. Subjects were randomly divided to intervention (n = 61) and placebo (n = 58) groups. Participants received capsules twice daily (500mgcapsules containing 350mgPistacia atlantica resin plus 150mgsugar in the interventiongroup, and 500 mg capsules containing 350 mg starch powder plus 150 mg sugar in the placebo group) for four weeks andthey were followed up for one month. The intensity and frequency of gastrointestinal symptoms, such as fullness, bloating, nausea, pain, and burning were assessed using the questionnaire on arrival, two and four weeks, and one month after the intervention. Results: Fifty-three patients in the PISTACIA atlantica group and 48 patients in the placebo group completed the study. The severityand frequency of gastrointestinal symptoms, such as early satiation nausea, pain, and burning were significantly decreased in thePistacia atlantica group. For example, severity of early satiation was 1. 67 0. 13 in PISTACIA and 2. 54 0. 17 in placebo groups in eightweeks (P > 0. 001) and frequency of this symptom was 2. 39 0. 27 and 4. 41 0. 34 in PISTACIA and placebo groups, respectively, ineight weeks (P > 0. 001), which was significantly decreased in the PISTACIA group. No serious adverse effects were reported. Conclusions: This study revealed that PISTACIA atlantica is significantly effective in functional DYSPEPSIA symptoms.

Cites

Effects of Pistacia lentiscus and Coriander Triphala on Adult Gastroesophageal Reflux Disease: A Randomized Double-Blinded Clinical Trial

References

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APA: Copy

EFTEKHARAFZALI, MAHDIYEHSADAT, MEHRABANI, MITRA, TAJADINI, HALEH, AHMADI, BIJAN, & ZAHEDI, MOHAMMAD JAVAD. (2018). EFFECT OF “ PISTACIA ATLANTICA” RESIN (BANEH) ON FUNCTIONAL DYSPEPSIA: ADOUBLE-BLIND, RANDOMIZED CLINICAL STUDY. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), 20(7), 0-0. SID. https://sid.ir/paper/293793/en

Vancouver: Copy

EFTEKHARAFZALI MAHDIYEHSADAT, MEHRABANI MITRA, TAJADINI HALEH, AHMADI BIJAN, ZAHEDI MOHAMMAD JAVAD. EFFECT OF “ PISTACIA ATLANTICA” RESIN (BANEH) ON FUNCTIONAL DYSPEPSIA: ADOUBLE-BLIND, RANDOMIZED CLINICAL STUDY. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ)[Internet]. 2018;20(7):0-0. Available from: https://sid.ir/paper/293793/en

IEEE: Copy

MAHDIYEHSADAT EFTEKHARAFZALI, MITRA MEHRABANI, HALEH TAJADINI, BIJAN AHMADI, and MOHAMMAD JAVAD ZAHEDI, “EFFECT OF “ PISTACIA ATLANTICA” RESIN (BANEH) ON FUNCTIONAL DYSPEPSIA: ADOUBLE-BLIND, RANDOMIZED CLINICAL STUDY,” IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), vol. 20, no. 7, pp. 0–0, 2018, [Online]. Available: https://sid.ir/paper/293793/en

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