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Information Journal Paper

Title

In Vivo Confocal Microscopic Analysis of Keratitis Induced by Anaphylaxis to Intravenous Metronidazole: A Case Report and Literature Review

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  0-0

Abstract

 Introduction: Keratitis induced by type I hypersensitivity to Metronidazole is rarely reported. In vivo Confocal Microscopy (IVCM) is a promisingmethodfor the investigation of corneal morphology under pathological conditions. The purpose of the present study was to investigate the IVCM features of Keratitis associated with Anaphylaxis to Metronidazole and review the literature regarding IVCM application to study drug-related changes in the cornea. Case Presentation: A 50-year-old woman with acute bilateral Keratitis induced by Anaphylaxis to intravenous Metronidazole presented to the Department of Ophthalmology, the first affiliated hospital of Jilin University, Changchun, China in Jan 2018. She initially experienced photophobia, moderate conjunctival injection, and watery discharge after infusion of intravenous Metronidazole. These symptoms gradually resolved one month after she was administered anti-allergic drugs. Corneal morphology related to Anaphylaxis to Metronidazole was investigated by IVCM before and after treatment. To our knowledge, this is the first reported case of IVCM images of Keratitis associated with Anaphylaxis to Metronidazole. Conclusions: In vivo Confocal Microscopy can allow objective evaluation of treatment response through cellular changes in the cornea and could provide good-quantity images of ocular surface tissues for follow-up.

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    APA: Copy

    Lu, Cheng Wei, Cui, Zhi Hua, Qi, Xiao Feng, Pant, Om Prakash, Lu, Cheng Bo, Hao, Ji Long, & Zhou, Dan Dan. (2019). In Vivo Confocal Microscopic Analysis of Keratitis Induced by Anaphylaxis to Intravenous Metronidazole: A Case Report and Literature Review. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), 21(1), 0-0. SID. https://sid.ir/paper/293846/en

    Vancouver: Copy

    Lu Cheng Wei, Cui Zhi Hua, Qi Xiao Feng, Pant Om Prakash, Lu Cheng Bo, Hao Ji Long, Zhou Dan Dan. In Vivo Confocal Microscopic Analysis of Keratitis Induced by Anaphylaxis to Intravenous Metronidazole: A Case Report and Literature Review. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ)[Internet]. 2019;21(1):0-0. Available from: https://sid.ir/paper/293846/en

    IEEE: Copy

    Cheng Wei Lu, Zhi Hua Cui, Xiao Feng Qi, Om Prakash Pant, Cheng Bo Lu, Ji Long Hao, and Dan Dan Zhou, “In Vivo Confocal Microscopic Analysis of Keratitis Induced by Anaphylaxis to Intravenous Metronidazole: A Case Report and Literature Review,” IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), vol. 21, no. 1, pp. 0–0, 2019, [Online]. Available: https://sid.ir/paper/293846/en

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