مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

ULCERATIVE COLITIS AND HLA CLASS II PHENOTYPING IN IRAN

Pages

  7-10

Abstract

 Ulcerative colitis (UC) is a nonspecific acute and chronic inflammatory bowel disease that diffusely involves the colonic mucosa. The etiology of UC has not yet been elucidated fully. However, many studies have found that immunologic disorders may play a role in the pathogenesis of UC. In addition, due to an increased frequency of UC in families, especially an increased monozygotic compared with dizygotic twin concordance, many implicate genetic factors in the development and regulation of the immune responses, such as the HLA class II genes, as candidates for conferring the genetic susceptibility. We studied the distribution of HLADR and DQ antigens and duration of sickness in 42 Iranian patients suffering from UC using the standard microlymphocytotoxicity technique. The phenotypic frequencies of HLA-DR2 were present in 24 of 84 controls and 18 of 42 patients (p= 0.24, corrected p, not significant). The present study reveals no association between HLA class n antigens ana UC, suggesting that the HLA-DR2 is not a predominant susceptibility gene for UC in the population studied.

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    APA: Copy

    FOROUTAN, H., NIKBIN, B., ANANI SARAB, GH., & KHOSRAVI, F.. (2001). ULCERATIVE COLITIS AND HLA CLASS II PHENOTYPING IN IRAN. MEDICAL JOURNAL OF THE ISLAMIC REPUBLIC OF IRAN (MJIRI), 15(1), 7-10. SID. https://sid.ir/paper/293905/en

    Vancouver: Copy

    FOROUTAN H., NIKBIN B., ANANI SARAB GH., KHOSRAVI F.. ULCERATIVE COLITIS AND HLA CLASS II PHENOTYPING IN IRAN. MEDICAL JOURNAL OF THE ISLAMIC REPUBLIC OF IRAN (MJIRI)[Internet]. 2001;15(1):7-10. Available from: https://sid.ir/paper/293905/en

    IEEE: Copy

    H. FOROUTAN, B. NIKBIN, GH. ANANI SARAB, and F. KHOSRAVI, “ULCERATIVE COLITIS AND HLA CLASS II PHENOTYPING IN IRAN,” MEDICAL JOURNAL OF THE ISLAMIC REPUBLIC OF IRAN (MJIRI), vol. 15, no. 1, pp. 7–10, 2001, [Online]. Available: https://sid.ir/paper/293905/en

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    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
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