MAGNESIUM SULFATE REDUCES POSTOPERATIVE PAIN

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JALALI A.

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Journal Paper

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Journal: Medical Journal of The Islamic Republic of Iran Year:2003 | Volume:17 | Issue:2 Page(s): 117-122

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Title

MAGNESIUM SULFATE REDUCES POSTOPERATIVE PAIN

Author(s)

JALALI A.

Keywords

MAGNESIUM SULFATE

POSTOPERATIVE PAIN

ANALGESIA.

Abstract

Pain has many adverse effects on all organ systems and its role is more important
in postoperative conditions. Use of opioids for pain management results
in various complications. MAGNESIUM SULFATE may play a role in postoperative
pain management and reduce the opioid-consumption trend. We assessed this
effect of MAGNESIUM SULFATE.
In a double blind randomized clinical trial 54 male patients in ASA class I
undergoing general anesthesia for elective unilateral inguinal herniorrhaphy were
randomly allocated in two equal groups who received 15mL of 20% magnesium
sulfate (cases) or 15 mL saline (controls) intravenously after anesthesia induction.
Surgical team and anesthetic protocol were identical. We measured postoperatively
the intensity of pain [according to visual analog pain score(VAS)] in the
first, 6th. 12th,and 24th hour after surgery and pethidine administration (that was
prescribed on demand) during one day after surgery.
Cases showed less pain intensity in the 6th h (p=0.026), 12th h (p<0.001) and
24thh (p=0.028) postop and received less pethidine (p=0.027). Side effects were
statistically identical.
In conclusion, administration of intravenous MAGNESIUM SULFATE is associated
with less pain and fewer analgesic requirements without any increase in side
effects. MAGNESIUM SULFATE could be an interesting adjuvant for postoperative ANALGESIA.

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APA: Copy

JALALI, A.. (2003). MAGNESIUM SULFATE REDUCES POSTOPERATIVE PAIN. MEDICAL JOURNAL OF THE ISLAMIC REPUBLIC OF IRAN (MJIRI), 17(2), 117-122. SID. https://sid.ir/paper/293917/en

Vancouver: Copy

JALALI A.. MAGNESIUM SULFATE REDUCES POSTOPERATIVE PAIN. MEDICAL JOURNAL OF THE ISLAMIC REPUBLIC OF IRAN (MJIRI)[Internet]. 2003;17(2):117-122. Available from: https://sid.ir/paper/293917/en

IEEE: Copy

A. JALALI, “MAGNESIUM SULFATE REDUCES POSTOPERATIVE PAIN,” MEDICAL JOURNAL OF THE ISLAMIC REPUBLIC OF IRAN (MJIRI), vol. 17, no. 2, pp. 117–122, 2003, [Online]. Available: https://sid.ir/paper/293917/en

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