PREVALENCE OF DELTA AGENT SUPER-INFECTION AND CO-INFECTION AMONG HBSAG-POSITIVE PATIENTS REFERRING TO REFERENCE IBTO LAB

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AMINI KAFIABAD S.; TAGHI NIA A.; KHAN BABA F.; TALEBIAN A.

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Journal: HAKIM RESEARCH JOURNAL Year:2007 | Volume:9 | Issue:4 Page(s): 7-11

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Information Journal Paper

Title

PREVALENCE OF DELTA AGENT SUPER-INFECTION AND CO-INFECTION AMONG HBSAG-POSITIVE PATIENTS REFERRING TO REFERENCE IBTO LAB

Author(s)

AMINI KAFIABAD S. | TAGHI NIA A. | KHAN BABA F. | TALEBIAN A. | Issue Writer Certificate

Keywords

DELTA HEPATITISQ3

HEPATITIS BQ3

CO-INFECTIONQ3

SUPER-INFECTIONQ3

Abstract

The hepatitis D virus (HDV) is a 36-nm virus, which needs HEPATITIS B virus for replication. Infection by the Delta agent can occur as a CO-INFECTION with HEPATITIS B, which usually causes acute hepatitis, or as a super- infection of HEPATITIS B infection. The present study was conducted to estimate the prevalence of super infection or CO-INFECTION in HBsAg positive patients.Methods: Anti-HDV (IgM) and HDV Ag by EIA method were tested in 79 HBsAg-positive sera and the liver function tests including SGOT and SGPT were done. All anti-HDV IgM positive samples were tested for anti-HBc IgM by EIA method. The prevalence of super infection was determined.Results: Delta Ag was not detected in any of the 79 sera. 7 out of 79 (8.8%) samples were positive for anti-HDV (IgM) but they were all negative for anti-HBc IgM. The liver enzyme function tests were elevated in 5 out of 6 samples.Conclusion: 7 samples were positive for anti-HDV (IgM) and indicated recent infection with HDV in these patients, but anti-HBc (IgM) was not detected, so these serologic data suggest SUPER-INFECTION with Delta agent in HBV-infected patients. In HBsAg-positive patients with liver enzyme elevation, investigating possible HDV infection is strongly recommended.

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APA: Copy

AMINI KAFIABAD, S., TAGHI NIA, A., KHAN BABA, F., & TALEBIAN, A.. (2007). PREVALENCE OF DELTA AGENT SUPER-INFECTION AND CO-INFECTION AMONG HBSAG-POSITIVE PATIENTS REFERRING TO REFERENCE IBTO LAB. HAKIM RESEARCH JOURNAL, 9(4), 7-11. SID. https://sid.ir/paper/29434/en

Vancouver: Copy

AMINI KAFIABAD S., TAGHI NIA A., KHAN BABA F., TALEBIAN A.. PREVALENCE OF DELTA AGENT SUPER-INFECTION AND CO-INFECTION AMONG HBSAG-POSITIVE PATIENTS REFERRING TO REFERENCE IBTO LAB. HAKIM RESEARCH JOURNAL[Internet]. 2007;9(4):7-11. Available from: https://sid.ir/paper/29434/en

IEEE: Copy

S. AMINI KAFIABAD, A. TAGHI NIA, F. KHAN BABA, and A. TALEBIAN, “PREVALENCE OF DELTA AGENT SUPER-INFECTION AND CO-INFECTION AMONG HBSAG-POSITIVE PATIENTS REFERRING TO REFERENCE IBTO LAB,” HAKIM RESEARCH JOURNAL, vol. 9, no. 4, pp. 7–11, 2007, [Online]. Available: https://sid.ir/paper/29434/en

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