FONNULATION, PREPARATION AND PHYSICO-CHEMICAL CONTROL OF VAGINAL SUPPOSITORIES CONTAINING VOLATILE OILS OF ALLIUM SATIVUM AND ZATARIA MULTIFLORA

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

ABOU FAZELI R.; MOSADEGH M.; VAHIDI H.; SHAFAATI A.; NADER N.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Hakim Journal Year:2000 | Volume:3 | Issue:3 Page(s): 231-243

Download Full-Text

Persian Verion

View:

6,539

Download:

Cites:

Information Journal Paper

Title

FONNULATION, PREPARATION AND PHYSICO-CHEMICAL CONTROL OF VAGINAL SUPPOSITORIES CONTAINING VOLATILE OILS OF ALLIUM SATIVUM AND ZATARIA MULTIFLORA

Author(s)

Keywords

VULVOVAGINAL CANDIDIASISQ4

CANDIDA ALBICANSQ4

ANTIFUNGAL EFFECTSQ4

ALLIUM SATIVUM VOLATILE OILQ4

ZATARIA MULTIJLORA VOLATILE OILQ4

VAGINAL SUPPOSITORYQ4

Abstract

VULVOVAGINAL CANDIDIASIS is, most commonly caused by CANDIDA ALBICANS. Due to the high incidence of this fungal infection and the antifungal activities of Allium sativum and Zataria multiflora, the preparation of vaginal suppositories containing their volatile oils, has been considered as the main goal of this investigation. The constituents of the volatile oils of Allium sativum (A.S. oil) and Zataria multiflora (Z.Moil) were identified by Gas Chromatography with mass spectrometry. Then the minimum inhibitory concentration of each volatile oil and their combinations were determined by the disk plate and cup plate methods. Vaginal suppositories containing 30 µl Z.M. oil and 15 pi mixture of A.S. oil-Z.M. oil per ml of base (polyethylene glycol) were prepared and their appearance, mass uniformity, hardness, disintegration time, content and unifonnity were evaluated. The stability of suppositories containing Z.M. oil, stored at 4, 25 and 40°C was investigated after 1, 2, and 6 months, while the stability of those containing both A.S. oil and Z.M. oil was studied after a 3 month-storage at 4°C 1rwas found that storage at higher temperatures (25 and 40° C) can cause a decrease in the voatile oil concentration. Since both A.S. and Z.M. oils have relevant in vitro antifungal activities against CANDIDA ALBICANS with low amounts, and due to the high quality of the formulated suppositories, these could be suggested as a successful replacement in the treatment of vaginitis caused by CANDIDA ALBICANS, following the clinical studies.

Cites

No record.

References

No record.

Cite

APA: Copy

ABOU FAZELI, R., MOSADEGH, M., VAHIDI, H., SHAFAATI, A., & NADER, N.. (2000). FONNULATION, PREPARATION AND PHYSICO-CHEMICAL CONTROL OF VAGINAL SUPPOSITORIES CONTAINING VOLATILE OILS OF ALLIUM SATIVUM AND ZATARIA MULTIFLORA. HAKIM RESEARCH JOURNAL, 3(3), 231-243. SID. https://sid.ir/paper/29505/en

Vancouver: Copy

ABOU FAZELI R., MOSADEGH M., VAHIDI H., SHAFAATI A., NADER N.. FONNULATION, PREPARATION AND PHYSICO-CHEMICAL CONTROL OF VAGINAL SUPPOSITORIES CONTAINING VOLATILE OILS OF ALLIUM SATIVUM AND ZATARIA MULTIFLORA. HAKIM RESEARCH JOURNAL[Internet]. 2000;3(3):231-243. Available from: https://sid.ir/paper/29505/en

IEEE: Copy

R. ABOU FAZELI, M. MOSADEGH, H. VAHIDI, A. SHAFAATI, and N. NADER, “FONNULATION, PREPARATION AND PHYSICO-CHEMICAL CONTROL OF VAGINAL SUPPOSITORIES CONTAINING VOLATILE OILS OF ALLIUM SATIVUM AND ZATARIA MULTIFLORA,” HAKIM RESEARCH JOURNAL, vol. 3, no. 3, pp. 231–243, 2000, [Online]. Available: https://sid.ir/paper/29505/en

Related Journal Papers