SHORT COMMUNICATION: PREGNANCY OUTCOMES IN WOMEN WITH IDIOPATHIC THROMBOCYTOPENIC PURPURA

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YASSAEE FAKHROLMOLOUK; ESKANDARI ROGHIEH; AMIRI ZOHREH

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Journal Paper

Paper Information

Journal: International Journal of Reproductive BioMedicine Year:2012 | Volume:10 | Issue:5 Page(s): 489-492

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Title

SHORT COMMUNICATION: PREGNANCY OUTCOMES IN WOMEN WITH IDIOPATHIC THROMBOCYTOPENIC PURPURA

Author(s)

YASSAEE FAKHROLMOLOUK | ESKANDARI ROGHIEH | AMIRI ZOHREH | Issue Writer Certificate

Keywords

PREGNANCY OUTCOMES

IDIOPATHIC THROMBOCYTOPENIC PURPURA

NEONATAL OUTCOME

Abstract

Background: IDIOPATHIC THROMBOCYTOPENIC PURPURA (ITP) is a disease that commonly affects women of reproductive age and is associated with maternal and fetal complications.Objective: The aim of the present study was to report the perinatal outcome in pregnant women with ITP.Materials and Methods: Twenty one pregnant women with ITP admitted in a teaching hospital in Tehran, from October 2008 to February 2010, were enrolled in this prospective historical cohort study; course and perinatal outcome of pregnancies were studied.Results: Seven (33.3%) cases had been diagnosed before pregnancy, while the other fourteen (66.7%) were diagnosed during pregnancy. During hospitalization, thirteen (62%) patients required treatment, eight (61.5%) of them with steroids, two (15.3%) received intravenous immunoglobulin (IVIG), and three (23%) were treated with steroids and IVIG. Three babies were delivered vaginally (14.3%), seventeen (81%) through cesarean section and one patient aborted her fetus. Nine mothers (42.9%) had platelet counts<50000/ml at the time of delivery; but postpartum hemorrhage occurred in 4 (19%) women and one women received platelet transfusion during cesarean section. Six (28.6%) women developed gestational diabetes. Pregnancy was complicated by preeclampsia in one woman and by abruptio placenta in another. One pregnancy terminated in intrauterine fetal death. Seventeen infants (89.5%) had normal platelet counts, and two (10.5%) had moderate thrombocytopenia. No infant showed signs of hemorrhage, but 2 neonates (10.5%) were diagnosed with intrauterine growth restriction.Conclusion: Rate of gestational diabetes in pregnant women with ITP is higher than the general population. Rate of gestinational diabetes is 3-5% and postpartum hemorrhage is 5-7% in general. Postpartum hemorrhage is common in these women. Severe thrombocytopenia and bleeding in the newborns are uncommon.

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APA: Copy

YASSAEE, FAKHROLMOLOUK, ESKANDARI, ROGHIEH, & AMIRI, ZOHREH. (2012). SHORT COMMUNICATION: PREGNANCY OUTCOMES IN WOMEN WITH IDIOPATHIC THROMBOCYTOPENIC PURPURA. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), 10(5), 489-492. SID. https://sid.ir/paper/295917/en

Vancouver: Copy

YASSAEE FAKHROLMOLOUK, ESKANDARI ROGHIEH, AMIRI ZOHREH. SHORT COMMUNICATION: PREGNANCY OUTCOMES IN WOMEN WITH IDIOPATHIC THROMBOCYTOPENIC PURPURA. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE)[Internet]. 2012;10(5):489-492. Available from: https://sid.ir/paper/295917/en

IEEE: Copy

FAKHROLMOLOUK YASSAEE, ROGHIEH ESKANDARI, and ZOHREH AMIRI, “SHORT COMMUNICATION: PREGNANCY OUTCOMES IN WOMEN WITH IDIOPATHIC THROMBOCYTOPENIC PURPURA,” INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), vol. 10, no. 5, pp. 489–492, 2012, [Online]. Available: https://sid.ir/paper/295917/en

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