ASSOCIATION BETWEEN Y-CHROMOSOME AZFC REGION MICRO-DELETIONS WITH RECURRENT MISCARRIAGE

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SOLEIMANIAN SAEEDE; KALANTAR SEYYED MAHDI; SHEIKHHA MOHAMMAD HASAN; ZAIMY MOHAMMAD ALI; RASTI AZAM; FAZLI HOSSEIN

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: International Journal of Reproductive BioMedicine Year:2013 | Volume:11 | Issue:5 Page(s): 431-434

Download Full-Text

View:

312

Download:

106

Cites:

Information Journal Paper

Title

ASSOCIATION BETWEEN Y-CHROMOSOME AZFC REGION MICRO-DELETIONS WITH RECURRENT MISCARRIAGE

Author(s)

Keywords

RECURRENT ABORTION

Y-CHROMOSOME MICRO DELETIONS

MULTIPLEX PCR

Abstract

Background: In human, about 25% of implanted embryos are losing 1-2 week following attachment to the uterus. A subset of this population will have three or more consecutive miscarriages which define as repeated pregnancy loss (RPL). Introducing the assisted reproductive technologies (ARTS) made a chance for infertile couples to solve their childless problem.Objective: This study was conducted to evaluate the incidence of Y-chromosome AZF region’s micro-deletions in male partners of couples with recurrent miscarriage (RM).Materials and Methods: Thirty male partner of couples with RM and thirty infertile males, who referred to the Yazd Research and Clinical Center for Infertility were recruited to this study. In addition, 30 healthy men were screened as a control group from the same center. After DNA extraction using salting out method, the multiplex-PCR was done for amplifying 8 known STSs proximal to the AZF region of the Y-chromosome. The results were compared between the groups using Fisher’s exact t-test and p<0.05 was considered statistically significant.Results: Of the 30 infertile males, 5 (16.6%) cases were associated with the AZF region micro-deletions of DYF87S, DYF84S1, DYF83S1 and DYF51S1, STSs. But in the fertile and RM male groups was found no deletions similar to those, of the infertile males (p=1.0). Instead 4 (13.3%) cases of the RM group males had different micro-deletions included DYS220 (AZFb, sY129), DYS262, DYF8551, and DYF8651, STSs. The AZFc locus of Y-chromosome micro-deletions have a significant role in RM (p=0.045).Conclusion: It seems that the Y-chromosome AZF region’s micro-deletions are associated with RM, and we recommend adding this AZF region STSs into infertility analyzing panels.

Cites

THE RELATION BETWEEN Y CHROMOSOME MICRODELETIONS AND RECURRENT PREGNANCY LOSS

References

No record.

Cite

APA: Copy

SOLEIMANIAN, SAEEDE, KALANTAR, SEYYED MAHDI, SHEIKHHA, MOHAMMAD HASAN, ZAIMY, MOHAMMAD ALI, RASTI, AZAM, & FAZLI, HOSSEIN. (2013). ASSOCIATION BETWEEN Y-CHROMOSOME AZFC REGION MICRO-DELETIONS WITH RECURRENT MISCARRIAGE. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), 11(5), 431-434. SID. https://sid.ir/paper/296016/en

Vancouver: Copy

SOLEIMANIAN SAEEDE, KALANTAR SEYYED MAHDI, SHEIKHHA MOHAMMAD HASAN, ZAIMY MOHAMMAD ALI, RASTI AZAM, FAZLI HOSSEIN. ASSOCIATION BETWEEN Y-CHROMOSOME AZFC REGION MICRO-DELETIONS WITH RECURRENT MISCARRIAGE. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE)[Internet]. 2013;11(5):431-434. Available from: https://sid.ir/paper/296016/en

IEEE: Copy

SAEEDE SOLEIMANIAN, SEYYED MAHDI KALANTAR, MOHAMMAD HASAN SHEIKHHA, MOHAMMAD ALI ZAIMY, AZAM RASTI, and HOSSEIN FAZLI, “ASSOCIATION BETWEEN Y-CHROMOSOME AZFC REGION MICRO-DELETIONS WITH RECURRENT MISCARRIAGE,” INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), vol. 11, no. 5, pp. 431–434, 2013, [Online]. Available: https://sid.ir/paper/296016/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops