PREVALENCE OF INTRATUBULAR GERM CELL NEOPLASIA IN CRYPTORCHID TESTES OF INFERTILE MEN

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POURKERAMATI FATEMEH; SOLTAN GHORAEI HALEH; AMIRJANNATI NASER; AKHONDI MOHAMMAD MEHDI; KHORRAM KHORSHID HAMID REZA

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Journal: International Journal of Reproductive BioMedicine Year:2013 | Volume:11 | Issue:4 Page(s): 339-342

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Title

PREVALENCE OF INTRATUBULAR GERM CELL NEOPLASIA IN CRYPTORCHID TESTES OF INFERTILE MEN

Author(s)

Keywords

CRYPTORCHIDISM

GERM CELL NEOPLASM

PLACENTAL LIKE ACID PHOSPHATASE

Abstract

Background: CRYPTORCHIDISM is a common malformation in neonates; surgery or medical treatments are applied during childhood. Untreated cryptorchid testes are in the risk of intratubular germ cell neoplasia (IGCN) and consequently invasive testicular tumors which could be shown by immunohistochemistry staining for PLACENTAL LIKE ACID PHOSPHATASE (PLAP) marker.Objective: We designed this study to know the prevalence of IGCN in untreated cryptorchid testes of infertile men, in our infertility center as a refferal center.Materials and Methods: In this cross-sectional study we assessed H&E slides of testicular samples of 13 adult infertile patients with impalpable intra-abdominal testes seeking infertility treatment; then we stained them by PLAP marker. Results: Three (23.08%) samples were positive for PLAP marker means presence of IGCN in testis. One of them showed seminoma besides IGCN.Conclusion: According to the results of this study and the fact that there are adult untreated cryptorchid patients in our country yet, it is suggested to pay more attention in clinical examination, assessment and follow up of such patients for malignancy screening.

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APA: Copy

POURKERAMATI, FATEMEH, SOLTAN GHORAEI, HALEH, AMIRJANNATI, NASER, AKHONDI, MOHAMMAD MEHDI, & KHORRAM KHORSHID, HAMID REZA. (2013). PREVALENCE OF INTRATUBULAR GERM CELL NEOPLASIA IN CRYPTORCHID TESTES OF INFERTILE MEN. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), 11(4), 339-342. SID. https://sid.ir/paper/296062/en

Vancouver: Copy

POURKERAMATI FATEMEH, SOLTAN GHORAEI HALEH, AMIRJANNATI NASER, AKHONDI MOHAMMAD MEHDI, KHORRAM KHORSHID HAMID REZA. PREVALENCE OF INTRATUBULAR GERM CELL NEOPLASIA IN CRYPTORCHID TESTES OF INFERTILE MEN. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE)[Internet]. 2013;11(4):339-342. Available from: https://sid.ir/paper/296062/en

IEEE: Copy

FATEMEH POURKERAMATI, HALEH SOLTAN GHORAEI, NASER AMIRJANNATI, MOHAMMAD MEHDI AKHONDI, and HAMID REZA KHORRAM KHORSHID, “PREVALENCE OF INTRATUBULAR GERM CELL NEOPLASIA IN CRYPTORCHID TESTES OF INFERTILE MEN,” INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), vol. 11, no. 4, pp. 339–342, 2013, [Online]. Available: https://sid.ir/paper/296062/en

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