THE ACCURACY OF PLACENTAL ALPHA-MICROGLOBULINE-1 TEST IN DIAGNOSIS OF PREMATURE RUPTURE OF THE MEMBRANES

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KHOOSHIDEH MARYAM; RADI VIDA; HOSSEINI REIHANEH; HOSSEINI LADAN

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Journal Paper

Paper Information

Journal: International Journal of Reproductive BioMedicine Year:2015 | Volume:13 | Issue:6 Page(s): 355-360

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Title

THE ACCURACY OF PLACENTAL ALPHA-MICROGLOBULINE-1 TEST IN DIAGNOSIS OF PREMATURE RUPTURE OF THE MEMBRANES

Author(s)

KHOOSHIDEH MARYAM | RADI VIDA | HOSSEINI REIHANEH | HOSSEINI LADAN | Issue Writer Certificate

Keywords

PLACENTAL ALPHA MICROGLOBULIN-1

PREMATURE RUPTURES OF MEMBRANE

DIAGNOSTIC TEST

Abstract

Background: Premature rupture of membranes (PROM) is a common obstetric issue during pregnancy which might lead to serious fetal or maternal problems. Therefore, an appropriate diagnosis and management of PROM are of significant importance in patients. Objective: The aim of this study was to determine the accuracy of placental alpha microglobuline-1 (PAMG-1) test in PROM diagnosis and compare this diagnostic method with other standard tests in diagnosis of PROM. Materials and Methods: In this prospective diagnostic accuracy study, patients with symptoms of membrane rupture in 16-39 weeks of gestation were involved. Three tests including Fern, Nitrazine and PAMG-1 were performed at the same time. Results: PROM was confirmed in 86 patients out of 100. The sensitivity and specificity were respectively 81.3% and 100% for Fern test, 93% and 92.8% for Nitrazine test, 98.9% and 92.8% for PAMG-1 test. PAMG-1 test showed higher sensitivity (98.9% with p<0.001) and accuracy (98%) compared with conventional tests. Although PAMG-1showed a lower positive predictive value (PPV) compared to conventional tests such as Fern test (100%), it was shown to be more accurate. Conclusion: The accuracy of PAMG-1 test was superior to both Fern and Nitrazine test in PROM diagnosis.

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APA: Copy

KHOOSHIDEH, MARYAM, RADI, VIDA, HOSSEINI, REIHANEH, & HOSSEINI, LADAN. (2015). THE ACCURACY OF PLACENTAL ALPHA-MICROGLOBULINE-1 TEST IN DIAGNOSIS OF PREMATURE RUPTURE OF THE MEMBRANES. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), 13(6), 355-360. SID. https://sid.ir/paper/296153/en

Vancouver: Copy

KHOOSHIDEH MARYAM, RADI VIDA, HOSSEINI REIHANEH, HOSSEINI LADAN. THE ACCURACY OF PLACENTAL ALPHA-MICROGLOBULINE-1 TEST IN DIAGNOSIS OF PREMATURE RUPTURE OF THE MEMBRANES. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE)[Internet]. 2015;13(6):355-360. Available from: https://sid.ir/paper/296153/en

IEEE: Copy

MARYAM KHOOSHIDEH, VIDA RADI, REIHANEH HOSSEINI, and LADAN HOSSEINI, “THE ACCURACY OF PLACENTAL ALPHA-MICROGLOBULINE-1 TEST IN DIAGNOSIS OF PREMATURE RUPTURE OF THE MEMBRANES,” INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), vol. 13, no. 6, pp. 355–360, 2015, [Online]. Available: https://sid.ir/paper/296153/en

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