OXIDATIVE STRESS AND ANTI-OXIDANT DEFENSE SYSTEM IN IRANIAN WOMEN WITH POLYCYSTIC OVARY SYNDROME (SHORT COMMUNICATION)

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MOTI MAHTAB; AMINI LEILA; MIRHOSEINI ARDAKANI SOHEILA SADAT; KAMALZADEH SARA; MASOOMIKARIMI MASOOMEH; JAFARISANI MOSLEM

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Journal: International Journal of Reproductive BioMedicine Year:2015 | Volume:13 | Issue:6 Page(s): 373-378

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Title

OXIDATIVE STRESS AND ANTI-OXIDANT DEFENSE SYSTEM IN IRANIAN WOMEN WITH POLYCYSTIC OVARY SYNDROME (SHORT COMMUNICATION)

Author(s)

Keywords

POLYCYSTIC OVARY SYNDROME

INFERTILITY

CRP

ANTIOXIDANT

AOPP

Abstract

Background: POLYCYSTIC OVARY SYNDROME (PCOS) is a common disorder of INFERTILITY which affects more than 100 million women. It is characterized by chronic anovulation, hyper androgenism and obesity. PCOS is also associated with oxidative stress changes. Objective: Here, we aimed to investigate the level of ANTIOXIDANTs and oxidative stress in Iranian women with PCOS as a predictive factor for cardiovascular disease for the first time in Iran. Materials and Methods: In this cross sectional study 30 women with PCOS and 30 healthy women were included. C-reactive protein, serum insulin, advanced oxidation protein products, and level of total ANTIOXIDANTs status were measured from blood samples. Results: The levels of serum insulin, C-reactive protein, advanced oxidation protein productswere significantly increased in women with PCOS compared with healthy women but there was a decrease in level of total ANTIOXIDANTs status in PCOS women. Conclusion: These changes show that oxidative stress contributes to PCOS and the decrease of ANTIOXIDANTs leads to increase of oxidation products contributing to PCOS.

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APA: Copy

MOTI, MAHTAB, AMINI, LEILA, MIRHOSEINI ARDAKANI, SOHEILA SADAT, KAMALZADEH, SARA, MASOOMIKARIMI, MASOOMEH, & JAFARISANI, MOSLEM. (2015). OXIDATIVE STRESS AND ANTI-OXIDANT DEFENSE SYSTEM IN IRANIAN WOMEN WITH POLYCYSTIC OVARY SYNDROME (SHORT COMMUNICATION). INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), 13(6), 373-378. SID. https://sid.ir/paper/296158/en

Vancouver: Copy

MOTI MAHTAB, AMINI LEILA, MIRHOSEINI ARDAKANI SOHEILA SADAT, KAMALZADEH SARA, MASOOMIKARIMI MASOOMEH, JAFARISANI MOSLEM. OXIDATIVE STRESS AND ANTI-OXIDANT DEFENSE SYSTEM IN IRANIAN WOMEN WITH POLYCYSTIC OVARY SYNDROME (SHORT COMMUNICATION). INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE)[Internet]. 2015;13(6):373-378. Available from: https://sid.ir/paper/296158/en

IEEE: Copy

MAHTAB MOTI, LEILA AMINI, SOHEILA SADAT MIRHOSEINI ARDAKANI, SARA KAMALZADEH, MASOOMEH MASOOMIKARIMI, and MOSLEM JAFARISANI, “OXIDATIVE STRESS AND ANTI-OXIDANT DEFENSE SYSTEM IN IRANIAN WOMEN WITH POLYCYSTIC OVARY SYNDROME (SHORT COMMUNICATION),” INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), vol. 13, no. 6, pp. 373–378, 2015, [Online]. Available: https://sid.ir/paper/296158/en

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