THE EFFECT OF LUTEAL PHASE GONADOTROPIN-RELEASING HORMONE ANTAGONIST ADMINISTRATION ON IVF OUTCOMES IN WOMEN AT RISK OF OHSS

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EFTEKHAR MARYAM; MIRAJ SEPIDEH; MORTAZAVIFAR ZAHRASADAT

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Journal Paper

Paper Information

Journal: International Journal of Reproductive BioMedicine Year:2016 | Volume:14 | Issue:8 Page(s): 507-510

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Title

THE EFFECT OF LUTEAL PHASE GONADOTROPIN-RELEASING HORMONE ANTAGONIST ADMINISTRATION ON IVF OUTCOMES IN WOMEN AT RISK OF OHSS

Author(s)

EFTEKHAR MARYAM | MIRAJ SEPIDEH | MORTAZAVIFAR ZAHRASADAT | Issue Writer Certificate

Keywords

GONADOTROPIN-RELEASING HORMONE ANTAGONIST

PREGNANCY OUTCOME

IN VITRO FERTILIZATION

Abstract

Background: Gonadotropin-releasing hormone (GnRH) plays essential roles in embryo implantation, invasion of trophoblastic tissue, and steroid synthesis in the placenta.Objective: The aim of this study was to evaluate the effect of GnRH antagonist administration on PREGNANCY OUTCOMEs in early implantation period.Materials and Methods: In this retrospective study, 94 infertile women undergoing GnRH antagonist protocol who were at risk of ovarian hyperstimulation syndrome (OHSS) were included. Sixty-seven patients (group I) received Cetrorelix 0.25 mg/daily in the luteal phase for 3 days while in 27 participants (group II), it was not administered. PREGNANCY OUTCOMEs were assessed based on chemical and clinical pregnancy rates.Results: The PREGNANCY OUTCOMEs were not significantly different between two groups (p=0.224).Conclusion: The present study proposed that luteal phase GnRH antagonist administration does not influence the chance of successful PREGNANCY OUTCOMEs.

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APA: Copy

EFTEKHAR, MARYAM, MIRAJ, SEPIDEH, & MORTAZAVIFAR, ZAHRASADAT. (2016). THE EFFECT OF LUTEAL PHASE GONADOTROPIN-RELEASING HORMONE ANTAGONIST ADMINISTRATION ON IVF OUTCOMES IN WOMEN AT RISK OF OHSS. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), 14(8), 507-510. SID. https://sid.ir/paper/296314/en

Vancouver: Copy

EFTEKHAR MARYAM, MIRAJ SEPIDEH, MORTAZAVIFAR ZAHRASADAT. THE EFFECT OF LUTEAL PHASE GONADOTROPIN-RELEASING HORMONE ANTAGONIST ADMINISTRATION ON IVF OUTCOMES IN WOMEN AT RISK OF OHSS. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE)[Internet]. 2016;14(8):507-510. Available from: https://sid.ir/paper/296314/en

IEEE: Copy

MARYAM EFTEKHAR, SEPIDEH MIRAJ, and ZAHRASADAT MORTAZAVIFAR, “THE EFFECT OF LUTEAL PHASE GONADOTROPIN-RELEASING HORMONE ANTAGONIST ADMINISTRATION ON IVF OUTCOMES IN WOMEN AT RISK OF OHSS,” INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), vol. 14, no. 8, pp. 507–510, 2016, [Online]. Available: https://sid.ir/paper/296314/en

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