Protective effects of curcumin co-treatment in rats with establishing chronic variable stress on testis and reproductive hormones

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MOHAMADPOUR MASOOMEH; NOORAFSHAN ALI; Karbalay Doust Saied; TALAEI KHOZANI TAHEREH; ALIABADI ELHAM

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: International Journal of Reproductive BioMedicine Year:2017 | Volume:15 | Issue:7 Page(s): 447-452

Download Full-Text

View:

287

Download:

Cites:

Information Journal Paper

Title

Protective effects of curcumin co-treatment in rats with establishing chronic variable stress on testis and reproductive hormones

Author(s)

Keywords

Testosterone

Follicle stimulating hormone

Luteinizing hormone

CVS

Curcumin

Abstract

Background: Protracted and repeated exposure to chronic variable stress (CVS) may lead to reproductive dysfunction. It is a basic cause of male infertility. Curcumin (CUR) is an active fraction of turmeric that used in traditional Chinese medicine. CUR represents various pharmacological activities. Objective: The purpose of this study was to determining the effects of CUR on testis and Testosterone, Follicle stimulating hormone (FSH) and Luteinizing hormone (LH) in rats with establishing chronic variable stress. Materials and Methods: Twenty-one adult male Sprague-Dawley rats were divided into three groups: 1) control, 2) CVS and 3) CVS+ CUR (100 mg/kg/day dissolved in 0. 5 mL of olive oil). All of the animals in control, CVS, and CVS+CUR groups were sacrificed after 15 days. Testosterone, FSH, LH, and testis damage were evaluated. Results: Significant changes in the normal range of Testosterone, FSH, LH serum levels and seminiferous tubule apoptotic cells were detected in CVS group compared to the control rats (p=0. 02). These parameters changed to a less extent in CVS+CUR animals compared to the CVS rats (p=0. 02). Conclusion: Our findings propose that Curcumin might have curative potential on the reproductive system function and its impairment. It’ s regulated by stress and reproductive-related hormones.

Cites