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Information Journal Paper

Title

The effect of Myo-inositol on sperm parameters and pregnancy rate in oligoasthenospermic men treated with IUI: A randomized clinical trial

Author(s)

 GHASEMI AFSANEH | AMJADI FATEMEHSADAT | Ghazi Mirsaeed Seyedeh Masoumeh | MOHAMMADBEIGI ROBABEH | GHASEMI SAMANEH | MORADI YOUSEF | Ghazi Mirsaeed Seyedeh Tahereh | Issue Writer Certificate 

Pages

  749-756

Abstract

 Background: In about 40% of the couples, the cause of infertility problems is attributed to men because of low Sperm production and disturbed Motility of Sperm. Pieces of evidence show that Myo-inositol has a potential role for the treatment of Sperm morphology and male fertility. Objective: This study aimed to determine the effect of Myo-inositol on the Sperm parameters and fertility rate in patients with oligoasthenoSpermia treated by intrauterine insemination (IUI). Materials and Methods: This study was a randomized clinical trial conducted on 37 patients with oligoasthenoSpermia treated by IUI during 2016-2017. In this study, the patients were randomly divided into two groups of oligoasthenoSpermia treated with (Case group) and without Myo-inositol (Control group). The case group received 0. 5 ml of Myo-inositol with a concentration of 2 mg/ml and incubated at 37° C incubator for 2 hr, but the control group had no interventions. Results: The results of this study showed that although there was no significant difference in Sperm parameters including Sperm Motility and concentration before processing with Myo-inositol in the case group, but there was a significant increase in Sperm Motility during the treatment with Myo-inositol. The therapeutic effect of this method was confirmed on induction of Pregnancy in 18% of the treated patients, in such a way that was about twice greater than those who did not receive the drug. Conclusion: According to the results of this study, the use of Myo-inositol is efficient enough to change Sperm parameters to increase the chance of fertility.

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    APA: Copy

    GHASEMI, AFSANEH, AMJADI, FATEMEHSADAT, Ghazi Mirsaeed, Seyedeh Masoumeh, MOHAMMADBEIGI, ROBABEH, GHASEMI, SAMANEH, MORADI, YOUSEF, & Ghazi Mirsaeed, Seyedeh Tahereh. (2019). The effect of Myo-inositol on sperm parameters and pregnancy rate in oligoasthenospermic men treated with IUI: A randomized clinical trial. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), 17(10), 749-756. SID. https://sid.ir/paper/296603/en

    Vancouver: Copy

    GHASEMI AFSANEH, AMJADI FATEMEHSADAT, Ghazi Mirsaeed Seyedeh Masoumeh, MOHAMMADBEIGI ROBABEH, GHASEMI SAMANEH, MORADI YOUSEF, Ghazi Mirsaeed Seyedeh Tahereh. The effect of Myo-inositol on sperm parameters and pregnancy rate in oligoasthenospermic men treated with IUI: A randomized clinical trial. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE)[Internet]. 2019;17(10):749-756. Available from: https://sid.ir/paper/296603/en

    IEEE: Copy

    AFSANEH GHASEMI, FATEMEHSADAT AMJADI, Seyedeh Masoumeh Ghazi Mirsaeed, ROBABEH MOHAMMADBEIGI, SAMANEH GHASEMI, YOUSEF MORADI, and Seyedeh Tahereh Ghazi Mirsaeed, “The effect of Myo-inositol on sperm parameters and pregnancy rate in oligoasthenospermic men treated with IUI: A randomized clinical trial,” INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), vol. 17, no. 10, pp. 749–756, 2019, [Online]. Available: https://sid.ir/paper/296603/en

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