Serum and Peritoneal Fluid Cytokine Profiles in Infertile Women with Endometriosis

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Tarokh Majid; GHAFFARI NOVIN MAREFAT; POORDAST TAHEREH; TAVANA ZOHREH; NAZARIAN HAMID; NOROUZIAN MOHSEN; GHARESI FARD BEHROUZ

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Journal of Immunology Year:2019 | Volume:16 | Issue:2 Page(s): 151-162

Download Full-Text

View:

176

Download:

172

Cites:

Information Journal Paper

Title

Serum and Peritoneal Fluid Cytokine Profiles in Infertile Women with Endometriosis

Author(s)

Keywords

Cytokines

Endometriosis

Infertility

T Cell Subsets

Abstract

Background: Endometriosis is a chronic inflammatory disease with the growth of endometrial cells out of uterus and in the peritoneal cavity. T Cell Subsets participate in the establishment and progress of the disease by producing different Cytokines. Objective: To investigate a group of Cytokines related to Th1/Th2/Th17/Treg subsets within both peripheral blood and peritoneal fluid (PF) samples from infertile Endometriosis women. Methods: Peripheral blood and PF samples were collected from 30 infertile Endometriosis and 30 non-Endometriosis fertile women during laparoscopy. Concentration of Cytokines, including TNF-α , IFN-γ , TGF-β 1, IL-4, IL-10, IL-17 and IL-23 were evaluated using ELISA method. Results: Results indicated that the concentration of IFN-γ within serum was significantly reduced in Endometriosis group (p=0. 001). Regarding PF Cytokines, TGF-β 1 was increased in Endometriosis group (p=0. 030). Furthermore, the ratios of IFN-γ /TGF- 1 and IL-17/IL-23 were significantly different between Endometriosis and non-Endometriosis women in serum samples (p<0. 001 and p<0. 01 respectively). The ratios of TNF-α /IL-10 and IL-17/IL-10 were also significantly different regarding PF samples between the two studied groups (p<0. 04 and p<0. 03 respectively). Finally, significant correlations were observed between the levels of IL-17 and IL-23, inflammatory and anti-inflammatory Cytokines, in both samples and serum to PF inflammatory Cytokines. Conclusion: Based on the results of the present study, in women with Endometriosis, the disturbance of Cytokines network might gradually activate the inflammatory responses and tissue repair, resulting in Endometriosis development after several years.

Cites

No record.

References

No record.

Cite

APA: Copy

Tarokh, Majid, GHAFFARI NOVIN, MAREFAT, POORDAST, TAHEREH, TAVANA, ZOHREH, NAZARIAN, HAMID, NOROUZIAN, MOHSEN, & GHARESI FARD, BEHROUZ. (2019). Serum and Peritoneal Fluid Cytokine Profiles in Infertile Women with Endometriosis. IRANIAN JOURNAL OF IMMUNOLOGY (IJI), 16(2), 151-162. SID. https://sid.ir/paper/296923/en

Vancouver: Copy

Tarokh Majid, GHAFFARI NOVIN MAREFAT, POORDAST TAHEREH, TAVANA ZOHREH, NAZARIAN HAMID, NOROUZIAN MOHSEN, GHARESI FARD BEHROUZ. Serum and Peritoneal Fluid Cytokine Profiles in Infertile Women with Endometriosis. IRANIAN JOURNAL OF IMMUNOLOGY (IJI)[Internet]. 2019;16(2):151-162. Available from: https://sid.ir/paper/296923/en

IEEE: Copy

Majid Tarokh, MAREFAT GHAFFARI NOVIN, TAHEREH POORDAST, ZOHREH TAVANA, HAMID NAZARIAN, MOHSEN NOROUZIAN, and BEHROUZ GHARESI FARD, “Serum and Peritoneal Fluid Cytokine Profiles in Infertile Women with Endometriosis,” IRANIAN JOURNAL OF IMMUNOLOGY (IJI), vol. 16, no. 2, pp. 151–162, 2019, [Online]. Available: https://sid.ir/paper/296923/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops