EFFICACY OF TINOSPORA CORDIFOLIA ON LEARNINGAND MEMORY IN HEALTHY VOLUNTEERS: A DOUBLE-BLIND, RANDOMIZED, PLACEBO CONTROLLED STUDY

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RAO Y.; KUMAR B.; BAIRY L.K.

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Journal: IRANIAN JOURNAL OF PHARMACOLOGY AND THERAPEUTICS (IJPT) Year:2004 | Volume:3 | Issue:2 Page(s): 57-60

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Title

EFFICACY OF TINOSPORA CORDIFOLIA ON LEARNINGAND MEMORY IN HEALTHY VOLUNTEERS: A DOUBLE-BLIND, RANDOMIZED, PLACEBO CONTROLLED STUDY

Author(s)

RAO Y. | KUMAR B. | BAIRY L.K. | Issue Writer Certificate

Keywords

LEARNING

MEMORY

TINOSPORA CORDIFOLIA

Abstract

Background: TINOSPORA CORDIFOLIA, an Indian medicinal plant, has been reported to have beneficial effects on disorders like peptic ulcer, hepatobiliary disorders, rheumatism, infectious diseases etc. It enhances cognition in normal rats and successfully overcomes cyclosporine induced MEMORY deficit. Methods: Thirty healthy volunteers of age 18-30 years received TINOSPORA CORDIFOLIA (500 mg of pure aqueous extract) or a matching placebo for 21 days in a double blind, randomized and placebo controlled design. LEARNING and MEMORY was assessed by subjecting the volunteers to a battery of psychological tests that aimed at studying visual MEMORY, logical MEMORY, verbal MEMORY, attention span and concentration. Results: TINOSPORA CORDIFOLIA showed a significant (p < 0.05) increase in the test scores for verbal LEARNING and MEMORY" (control -1.2±1.9, drug 6.9±2.5) and "logical MEMORY" (control 5.1±6.1, drug 26.6±6.7). No significant untoward effects were reported during TINOSPORA CORDIFOLIA treatment. Conclusion: TINOSPORA CORDIFOLIA, 500 mg daily, enhances verbal LEARNING and MEMORY and logical MEMORY (of immediate and short term type) compared to placebo in healthy volunteers.

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APA: Copy

RAO, Y., KUMAR, B., & BAIRY, L.K.. (2004). EFFICACY OF TINOSPORA CORDIFOLIA ON LEARNINGAND MEMORY IN HEALTHY VOLUNTEERS: A DOUBLE-BLIND, RANDOMIZED, PLACEBO CONTROLLED STUDY. IRANIAN JOURNAL OF PHARMACOLOGY AND THERAPEUTICS (IJPT), 3(2), 57-60. SID. https://sid.ir/paper/297059/en

Vancouver: Copy

RAO Y., KUMAR B., BAIRY L.K.. EFFICACY OF TINOSPORA CORDIFOLIA ON LEARNINGAND MEMORY IN HEALTHY VOLUNTEERS: A DOUBLE-BLIND, RANDOMIZED, PLACEBO CONTROLLED STUDY. IRANIAN JOURNAL OF PHARMACOLOGY AND THERAPEUTICS (IJPT)[Internet]. 2004;3(2):57-60. Available from: https://sid.ir/paper/297059/en

IEEE: Copy

Y. RAO, B. KUMAR, and L.K. BAIRY, “EFFICACY OF TINOSPORA CORDIFOLIA ON LEARNINGAND MEMORY IN HEALTHY VOLUNTEERS: A DOUBLE-BLIND, RANDOMIZED, PLACEBO CONTROLLED STUDY,” IRANIAN JOURNAL OF PHARMACOLOGY AND THERAPEUTICS (IJPT), vol. 3, no. 2, pp. 57–60, 2004, [Online]. Available: https://sid.ir/paper/297059/en

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