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Information Journal Paper

Title

BIOACTIVE ALKALOID FROM SIDA CORDIFOLIA LINN. WITH ANALGESIC AND ANTI-INFLAMMATORY ACTIVITIES

Pages

  175-178

Abstract

 In the present study, the ANALGESIC and ANTI-INFLAMMATORY activities of a new alkaloid (5′-Hydroxymethyl-1′- (1,2,3,9-tetrahydro-pyrrolo [2,1-b] quinazolin-1-yl)-heptan-1-one) (compound 1), isolated from Sida cordi- folia Linn. was investigated in animal models. The ANALGESIC activity was investigated in the acetic acid induced writhing and the radiant heat tail flick model in mice and the carrageen an induced rat paw edema  model was used for ANTI-INFLAMMATORY study. The compound produced significant (p<0.01) ANALGESIC activity in both models. The compound also exhibited significant (p<0.01) inhibition of rat paw edema induced by carrageen an. These results indicated that compound 1 possessed ANALGESIC and ANTI-INFLAMMATORY activities.

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    Cite

    APA: Copy

    SUTRADHAR, R.K., RAHMAN, A.K.M.M., AHMAD, M., CHANDRA BACHAR, S., SAHA, A., & GUHA, S.K.. (2006). BIOACTIVE ALKALOID FROM SIDA CORDIFOLIA LINN. WITH ANALGESIC AND ANTI-INFLAMMATORY ACTIVITIES. IRANIAN JOURNAL OF PHARMACOLOGY AND THERAPEUTICS (IJPT), 5(2), 175-178. SID. https://sid.ir/paper/297123/en

    Vancouver: Copy

    SUTRADHAR R.K., RAHMAN A.K.M.M., AHMAD M., CHANDRA BACHAR S., SAHA A., GUHA S.K.. BIOACTIVE ALKALOID FROM SIDA CORDIFOLIA LINN. WITH ANALGESIC AND ANTI-INFLAMMATORY ACTIVITIES. IRANIAN JOURNAL OF PHARMACOLOGY AND THERAPEUTICS (IJPT)[Internet]. 2006;5(2):175-178. Available from: https://sid.ir/paper/297123/en

    IEEE: Copy

    R.K. SUTRADHAR, A.K.M.M. RAHMAN, M. AHMAD, S. CHANDRA BACHAR, A. SAHA, and S.K. GUHA, “BIOACTIVE ALKALOID FROM SIDA CORDIFOLIA LINN. WITH ANALGESIC AND ANTI-INFLAMMATORY ACTIVITIES,” IRANIAN JOURNAL OF PHARMACOLOGY AND THERAPEUTICS (IJPT), vol. 5, no. 2, pp. 175–178, 2006, [Online]. Available: https://sid.ir/paper/297123/en

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