ANTINOCICEPTIVE ACTIVITY OF MIMOSA PUDICA LINN

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KARTHIKEYAN M.; DEEPA M.K.

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Journal Paper

Paper Information

Journal: IRANIAN JOURNAL OF PHARMACOLOGY AND THERAPEUTICS (IJPT) Year:2010 | Volume:9 | Issue:1 Page(s): 11-14

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Information Journal Paper

Title

ANTINOCICEPTIVE ACTIVITY OF MIMOSA PUDICA LINN

Author(s)

KARTHIKEYAN M. | DEEPA M.K. | Issue Writer Certificate

Keywords

MIMOSA PUDICA LINN

WHOLE PLANT

AQUEOUS EXTRACT

ANALGESIC ACTIVITY

WRITHING TEST

HOT PLATE TEST

Abstract

MIMOSA PUDICA LINN (Mimisoideae) is a plant used in traditional medicine for various disorders. The aim of this work was to evaluate the acute toxicity and antinociceptive activity of the AQUEOUS EXTRACT of Mimosa pudica in animal models. In the acute toxicity study, a single dose of AQUEOUS EXTRACT of 2000 mg kg-1 body weight p.o. was administered. For 48 h, animals showed no clinical signs and mortality. In the acetic acid-induced writhing model, the extract at a dose of 200 & 400 mg kg-1 body weight showed significant (p<0.001) inhibition of writhing response of 46.24 and 56.0% respectively. In the HOT PLATE TEST, the extract produced a significant (p<0.001) increase in the latency in a dose-related manner. This study established the analgesic properties of MIMOSA PUDICA LINN.

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APA: Copy

KARTHIKEYAN, M., & DEEPA, M.K.. (2010). ANTINOCICEPTIVE ACTIVITY OF MIMOSA PUDICA LINN. IRANIAN JOURNAL OF PHARMACOLOGY AND THERAPEUTICS (IJPT), 9(1), 11-14. SID. https://sid.ir/paper/297221/en

Vancouver: Copy

KARTHIKEYAN M., DEEPA M.K.. ANTINOCICEPTIVE ACTIVITY OF MIMOSA PUDICA LINN. IRANIAN JOURNAL OF PHARMACOLOGY AND THERAPEUTICS (IJPT)[Internet]. 2010;9(1):11-14. Available from: https://sid.ir/paper/297221/en

IEEE: Copy

M. KARTHIKEYAN, and M.K. DEEPA, “ANTINOCICEPTIVE ACTIVITY OF MIMOSA PUDICA LINN,” IRANIAN JOURNAL OF PHARMACOLOGY AND THERAPEUTICS (IJPT), vol. 9, no. 1, pp. 11–14, 2010, [Online]. Available: https://sid.ir/paper/297221/en

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