ANTIBACTERIAL ACTIVITY AND CYTOTOXICITY SCREENING OF SUMATRAN KADUK (PIPER SARMENTOSUM ROXB.)

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ATIAX E.; AHMAD F.; SIRAT H.M.; ARBAIN D.

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Journal Paper

Paper Information

Journal: IRANIAN JOURNAL OF PHARMACOLOGY AND THERAPEUTICS (IJPT) Year:2011 | Volume:10 | Issue:1 Page(s): 1-5

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Information Journal Paper

Title

ANTIBACTERIAL ACTIVITY AND CYTOTOXICITY SCREENING OF SUMATRAN KADUK (PIPER SARMENTOSUM ROXB.)

Author(s)

ATIAX E. | AHMAD F. | SIRAT H.M. | ARBAIN D. | Issue Writer Certificate

Keywords

PIPERACEAE

P. SARMENTOSUM

AMIDES

ANTIBACTERIAL

CYTOTOXICITY

Abstract

Phytochemical investigations of Piper sarmentosum Roxb., yielded four compounds; three AMIDES, identified as 3- (3’, 4’, 5’-trimethoxyphenylpropanoyl) pyrrolidine, 3- (4’-methoxyphenylpropanoyl) pyrrole, N-(3-phenylpropanoyl) pyrrole and a sterol namely b-sitosterol.3- (4’-Methoxyphenylpropanoyl) pyrrole was found for the first time in this Piper species. All chemical constituents were tested for their ANTIBACTERIAL activity using disk diffusion method and CYTOTOXICITY screening using sul-forhodamine B (SRB) assay. All of the compounds were found only active towards gram-positive bacteria except 3- (4’-methoxyphenylpropanoyl) pyrrole with no activity against both gram-positive and gram-negative bacteria. Meanwhile, the CYTOTOXICITY screening using SRB assay indicated that none of these compounds was active as an anticancer agent.

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APA: Copy

ATIAX, E., AHMAD, F., SIRAT, H.M., & ARBAIN, D.. (2011). ANTIBACTERIAL ACTIVITY AND CYTOTOXICITY SCREENING OF SUMATRAN KADUK (PIPER SARMENTOSUM ROXB.). IRANIAN JOURNAL OF PHARMACOLOGY AND THERAPEUTICS (IJPT), 10(1), 1-5. SID. https://sid.ir/paper/297227/en

Vancouver: Copy

ATIAX E., AHMAD F., SIRAT H.M., ARBAIN D.. ANTIBACTERIAL ACTIVITY AND CYTOTOXICITY SCREENING OF SUMATRAN KADUK (PIPER SARMENTOSUM ROXB.). IRANIAN JOURNAL OF PHARMACOLOGY AND THERAPEUTICS (IJPT)[Internet]. 2011;10(1):1-5. Available from: https://sid.ir/paper/297227/en

IEEE: Copy

E. ATIAX, F. AHMAD, H.M. SIRAT, and D. ARBAIN, “ANTIBACTERIAL ACTIVITY AND CYTOTOXICITY SCREENING OF SUMATRAN KADUK (PIPER SARMENTOSUM ROXB.),” IRANIAN JOURNAL OF PHARMACOLOGY AND THERAPEUTICS (IJPT), vol. 10, no. 1, pp. 1–5, 2011, [Online]. Available: https://sid.ir/paper/297227/en

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