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Information Journal Paper

Title

AMPICILLIN USAGE AND AMPICILLIN RESISTANT (AMPR) PLASMIDS MEDIATED ESCHERICHIA COLI ISOLATED FROM DIARRHEAGENIC PATIENTS ATTENDING SOME TEACHING HOSPITAL IN NIGERIA

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Abstract

 From 2001 to 2004, we carry on a survey on the utilization of ampicillin among some diarrheagenic patients attending some Teaching Hospitals in Nigeria. From the result 723(58.2%) volunteers responded to the questionnaires, where only 83(11.4%) consult a doctor for prescription, 397(54.9%) from drug retailers while 142(20.1%) self prescribe and 56(7.7%) prescription was base on the advice of friends and relatives. The results also indicate that 229 (31.7%) take full regimen if prescribed by a doctor and 494(68.3%) stop the consumption of the drug when the signs and symptoms subside. Of the 249 diarrheagenic clinical isolates of E coli strains obtained from 2001 to 2004, 78 (31.3%) were obtained from UBTH, 41(16.5%) from ABUTH, 38(15.3%) from NAUTH and 92(36.9%) from UCH with a mean average of 63(25.3%). Among the antibiotics tested, ampicillin was the least susceptible antibiotics while the quinolones were the most susceptible. Most of the E coli strains screened had one or more resistant R plasmids. 52% of the E coli harbour ampicillin resistant plasmids of different molecular weights that ranged from ≤0.451kbp to ≥1.254kbp. Mostly Chromosomal DNA mediated most of the E coli isolates resistant to tetracycline, erythromycin, and ciprofloxacin. None of the Teaching Hospital had a surveillance method for evaluating the emergence of resistance pathogens.

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    APA: Copy

    YAH, SC., EGHAFONA, N., ENABULELE, I., & ALUYI, H.. (2006). AMPICILLIN USAGE AND AMPICILLIN RESISTANT (AMPR) PLASMIDS MEDIATED ESCHERICHIA COLI ISOLATED FROM DIARRHEAGENIC PATIENTS ATTENDING SOME TEACHING HOSPITAL IN NIGERIA. SHIRAZ E MEDICAL JOURNAL, 7(4), 0-0. SID. https://sid.ir/paper/299429/en

    Vancouver: Copy

    YAH SC., EGHAFONA N., ENABULELE I., ALUYI H.. AMPICILLIN USAGE AND AMPICILLIN RESISTANT (AMPR) PLASMIDS MEDIATED ESCHERICHIA COLI ISOLATED FROM DIARRHEAGENIC PATIENTS ATTENDING SOME TEACHING HOSPITAL IN NIGERIA. SHIRAZ E MEDICAL JOURNAL[Internet]. 2006;7(4):0-0. Available from: https://sid.ir/paper/299429/en

    IEEE: Copy

    SC. YAH, N. EGHAFONA, I. ENABULELE, and H. ALUYI, “AMPICILLIN USAGE AND AMPICILLIN RESISTANT (AMPR) PLASMIDS MEDIATED ESCHERICHIA COLI ISOLATED FROM DIARRHEAGENIC PATIENTS ATTENDING SOME TEACHING HOSPITAL IN NIGERIA,” SHIRAZ E MEDICAL JOURNAL, vol. 7, no. 4, pp. 0–0, 2006, [Online]. Available: https://sid.ir/paper/299429/en

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