EXPLORING THE PROTECTIVE EFFECT OF ASCORBIC ACID AND AQUEOUS EXTRACT OF SPIRULINA PLATENSIS ON METHOTREXATE-INDUCED LIPID PEROXIDATION

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RAY S.; ROY K.; SENGUPTA C.

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Paper Information

Journal: IRANIAN JOURNAL OF PHARMACEUTICAL SCIENCES Year:2007 | Volume:3 | Issue:4 Page(s): 217-228

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Title

EXPLORING THE PROTECTIVE EFFECT OF ASCORBIC ACID AND AQUEOUS EXTRACT OF SPIRULINA PLATENSIS ON METHOTREXATE-INDUCED LIPID PEROXIDATION

Author(s)

RAY S. | ROY K. | SENGUPTA C. | Issue Writer Certificate

Keywords

ASCORBIC ACID

LIPID PEROXIDATION

METHOTREXATE

NITRIC OXIDE

REDUCED GLUTATHIONE

SPIRULINA PLATENSIS

Abstract

This study was designed to explore the protective effects of ASCORBIC ACID and water extract of SPIRULINA PLATENSIS (blue green algae) on METHOTREXATE-induced LIPID PEROXIDATION using goat liver as the lipid source. This in vitro evaluation was done by measuring the malondialdehyde, 4-hydroxy-2-nonenal, REDUCED GLUTATHIONE and NITRIC OXIDE content of tissue homogenates. The study reveals the LIPID PEROXIDATION induction capacity of METHOTREXATE, the anti-peroxidative potential of ASCORBIC ACID and aqueous extract of S. platensis on METHOTREXATE-induced LIPID PEROXIDATION.

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APA: Copy

RAY, S., ROY, K., & SENGUPTA, C.. (2007). EXPLORING THE PROTECTIVE EFFECT OF ASCORBIC ACID AND AQUEOUS EXTRACT OF SPIRULINA PLATENSIS ON METHOTREXATE-INDUCED LIPID PEROXIDATION. IRANIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 3(4), 217-228. SID. https://sid.ir/paper/300225/en

Vancouver: Copy

RAY S., ROY K., SENGUPTA C.. EXPLORING THE PROTECTIVE EFFECT OF ASCORBIC ACID AND AQUEOUS EXTRACT OF SPIRULINA PLATENSIS ON METHOTREXATE-INDUCED LIPID PEROXIDATION. IRANIAN JOURNAL OF PHARMACEUTICAL SCIENCES[Internet]. 2007;3(4):217-228. Available from: https://sid.ir/paper/300225/en

IEEE: Copy

S. RAY, K. ROY, and C. SENGUPTA, “EXPLORING THE PROTECTIVE EFFECT OF ASCORBIC ACID AND AQUEOUS EXTRACT OF SPIRULINA PLATENSIS ON METHOTREXATE-INDUCED LIPID PEROXIDATION,” IRANIAN JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 3, no. 4, pp. 217–228, 2007, [Online]. Available: https://sid.ir/paper/300225/en

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