The Relationship between Body Mass Index (BMI) and Depression According to the rs16139NPY Gene

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Dolatian Atieh; ARZAGHI SEYED MASOUD; QORBANI MOSTAFA; PISHVA HAMIDEH

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Journal Paper

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Journal: Iranian Journal of Psychiatry Year:2017 | Volume:12 | Issue:3 Page(s): 201-205

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Title

The Relationship between Body Mass Index (BMI) and Depression According to the rs16139NPY Gene

Author(s)

Dolatian Atieh | ARZAGHI SEYED MASOUD | QORBANI MOSTAFA | PISHVA HAMIDEH | Issue Writer Certificate

Keywords

Depression

NPY Polymorphism

Obesity

Body Mass Index (BMI)

rs16139NPY Gene

Abstract

Objective: Obesity and Depression are likely to interact mutually, which makes it unclear whether Obesity causes Depression or Depression leads to Obesity, and how the genotypes have a role in Obesity and Depression. Method: This cross-sectional study was conducted on a sample of 400 individuals from the participants in the third phase of the comprehensive Iranian Multicenter Osteoporosis Study (IMOS). Anthropometric measurements and Depression were assessed. PCR-RFLP was used to investigate the NPY Polymorphism. Binary logistic regression model was employed to determine Depression as the dependent factor and gene polymorphism. Results: The frequency of NPY rs16139 was 6%. No significant association was found between NPY genotypes and Depression (p >0. 05). Furthermore, the results suggest that those with central Obesity had an increased chance of developing Depression (P = 0. 02). Conclusion: The frequency of NPY Polymorphism was 6%. Our study could not find a correlation between rs16139 and Depression.

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APA: Copy

Dolatian, Atieh, ARZAGHI, SEYED MASOUD, QORBANI, MOSTAFA, & PISHVA, HAMIDEH. (2017). The Relationship between Body Mass Index (BMI) and Depression According to the rs16139NPY Gene. IRANIAN JOURNAL OF PSYCHIATRY, 12(3), 201-205. SID. https://sid.ir/paper/302465/en

Vancouver: Copy

Dolatian Atieh, ARZAGHI SEYED MASOUD, QORBANI MOSTAFA, PISHVA HAMIDEH. The Relationship between Body Mass Index (BMI) and Depression According to the rs16139NPY Gene. IRANIAN JOURNAL OF PSYCHIATRY[Internet]. 2017;12(3):201-205. Available from: https://sid.ir/paper/302465/en

IEEE: Copy

Atieh Dolatian, SEYED MASOUD ARZAGHI, MOSTAFA QORBANI, and HAMIDEH PISHVA, “The Relationship between Body Mass Index (BMI) and Depression According to the rs16139NPY Gene,” IRANIAN JOURNAL OF PSYCHIATRY, vol. 12, no. 3, pp. 201–205, 2017, [Online]. Available: https://sid.ir/paper/302465/en

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