ANTIMICROBIAL EFFICACY OF MINERAL TRIOXIDE AGGREGATE WITH AND WITHOUT SILVER NANOPARTICLES

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SAMIEI MOHAMMAD; AGHAZADEH MOHAMMAD; LOTFI MEHRDAD; SHAKOEI SAHAR; AGHAZADE ZAHRA; VAHID PAKDEL SEYYED MAHDI

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Journal Paper

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Journal: Iranian Endodontic Journal Year:2013 | Volume:8 | Issue:4 Page(s): 166-170

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Title

ANTIMICROBIAL EFFICACY OF MINERAL TRIOXIDE AGGREGATE WITH AND WITHOUT SILVER NANOPARTICLES

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Keywords

ANTIBACTERIAL AGENTS

ANTIFUNGAL AGENTS

MINERAL TRIOXIDE AGGREGATE

NANOPARTICLES

SILVER

Abstract

Introduction: Most current root-end filling materials do not provide a perfect seal. Thus, a microscopic space is likely to exist in the interface between walls of the root-end cavity and filling material, which allows microorganisms and their products to penetrate. In addition to good sealing ability and biocompatibility, root-end filling materials should ideally have some antimicrobial activity. Therefore, this in vitro study aimed to evaluate the antimicrobial properties of Angelus white MINERAL TRIOXIDE AGGREGATE (MTA) and the mixture of MTA with SILVER NANOPARTICLES (1% weight; MTA/SN). Materials and Methods: Antimicrobial properties of MTA and MTA/SN were tested by agar diffusion technique against Enterococcus faecalis, Pseudomonas aeruginosa, Staphylococcus aureus, and Candida albicans. The microbial inhibition zones around the materials were measured by a caliper with 0.1-mm accuracy.Student’s t-test was used for comparison between the two groups in normal data distribution and Man-Whitney U test for non-normal distribution.Results: Student’s t-test revealed that for E. faecalis, C. albicans, and P. aeruginosa, microbial inhibition zone of MTA/SN was significantly greater than that of MTA (P=0.000). Mann-Whitney U test indicated no significant difference between the effect of MTA and MTA/SN on S. aureus (P>0.05).Conclusion: Based on the results of this study, adding SILVER NANOPARTICLES to MTA improved its antimicrobial efficacy.

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APA: Copy

SAMIEI, MOHAMMAD, AGHAZADEH, MOHAMMAD, LOTFI, MEHRDAD, SHAKOEI, SAHAR, AGHAZADE, ZAHRA, & VAHID PAKDEL, SEYYED MAHDI. (2013). ANTIMICROBIAL EFFICACY OF MINERAL TRIOXIDE AGGREGATE WITH AND WITHOUT SILVER NANOPARTICLES. IRANIAN ENDODONTIC JOURNAL (IEJ), 8(4), 166-170. SID. https://sid.ir/paper/302854/en

Vancouver: Copy

SAMIEI MOHAMMAD, AGHAZADEH MOHAMMAD, LOTFI MEHRDAD, SHAKOEI SAHAR, AGHAZADE ZAHRA, VAHID PAKDEL SEYYED MAHDI. ANTIMICROBIAL EFFICACY OF MINERAL TRIOXIDE AGGREGATE WITH AND WITHOUT SILVER NANOPARTICLES. IRANIAN ENDODONTIC JOURNAL (IEJ)[Internet]. 2013;8(4):166-170. Available from: https://sid.ir/paper/302854/en

IEEE: Copy

MOHAMMAD SAMIEI, MOHAMMAD AGHAZADEH, MEHRDAD LOTFI, SAHAR SHAKOEI, ZAHRA AGHAZADE, and SEYYED MAHDI VAHID PAKDEL, “ANTIMICROBIAL EFFICACY OF MINERAL TRIOXIDE AGGREGATE WITH AND WITHOUT SILVER NANOPARTICLES,” IRANIAN ENDODONTIC JOURNAL (IEJ), vol. 8, no. 4, pp. 166–170, 2013, [Online]. Available: https://sid.ir/paper/302854/en

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