FREQUENCY AND CAUSES OF HYPOTONIA IN NEONATAL PERIOD WITH THE GESTATIONAL AGE OF MORE THAN 36 WEEKS IN NICU OF MOFID CHILDREN HOSPITAL, TEHRAN, IRAN DURING 2012-2014

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SEYED SHAHABI NOSRATOLLAH; FAKHRAEE Hossain; KAZEMIAN MOHAMMAD; Afjeh Abolfazl; FALLAHI MINOO; SHARIATI MARYAM; GORJI Fatemeh

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Journal: Iranian Journal of Child Neurology Year:2017 | Volume:11 | Issue:1 Page(s): 0-0

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Title

FREQUENCY AND CAUSES OF HYPOTONIA IN NEONATAL PERIOD WITH THE GESTATIONAL AGE OF MORE THAN 36 WEEKS IN NICU OF MOFID CHILDREN HOSPITAL, TEHRAN, IRAN DURING 2012-2014

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Keywords

NEONATAL HYPOTONIA

GENETIC

PERIPHERAL

CENTRAL

Abstract

ObjectiveHypotonia is a serious neurologic problem in neonatal period. Althoughhypotonia is a nonspecific clinical finding but it is the most common motordisorder in the newborn. The objective of this study was to determine thefrequency of NEONATAL HYPOTONIA then to ascertain of the most commoncauses.Materials & MethodsThis cross –sectional prospective study was carried out on the 3281 term infantshospitalized in conventional and NICU of Mofid Children Hospital, Tehran, Iran during 2012-2014. Diagnosis was made by history, physical & neurologicalexamination and accessible diagnostic tests.ResultsFifty nine hypotonic neonates were identified, forty seven (79.66%) hadcentral hypotonia (Hypoxic ischemic encephalopathy (n=2), other causes ofencephalopathy (n=2), intracranial hemorrhage (n=4), CNS abnormalities (n=7), chromosomal disorders (n=4), syndromic–nonsyndromic (n=8), and metabolicdiseases (n=8). PERIPHERAL hypotonic recognized in 6 infants (10.17%); spinalmuscular atrophy (n=1), and myopathy (n=5). Six cases (10.17%) remainedunclassified. Twelve infants had transient hypotonia. In final study, 18 of 59infants (30%) died, nearly 90% before one year of age. Twenty-eight (47%)infants found developmental disorders and only 13 (22%) infants achievednormal development in their follow up.ConclusionNEONATAL HYPOTONIA is a common event in neonatal period. A majority ofdiagnosis is obtained by history and physical examination. Neuroimaging, GENETIC and metabolic tests were also important in diagnosis. GENETIC, syndromic–nonsyndromic, and metabolic disorders were the most causes ofNEONATAL HYPOTONIA.

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APA: Copy

SEYED SHAHABI, NOSRATOLLAH, FAKHRAEE, Hossain, KAZEMIAN, MOHAMMAD, Afjeh, Abolfazl, FALLAHI, MINOO, SHARIATI, MARYAM, & GORJI, Fatemeh. (2017). FREQUENCY AND CAUSES OF HYPOTONIA IN NEONATAL PERIOD WITH THE GESTATIONAL AGE OF MORE THAN 36 WEEKS IN NICU OF MOFID CHILDREN HOSPITAL, TEHRAN, IRAN DURING 2012-2014. IRANIAN JOURNAL OF CHILD NEUROLOGY (IJCN), 11(1), 0-0. SID. https://sid.ir/paper/303520/en

Vancouver: Copy

SEYED SHAHABI NOSRATOLLAH, FAKHRAEE Hossain, KAZEMIAN MOHAMMAD, Afjeh Abolfazl, FALLAHI MINOO, SHARIATI MARYAM, GORJI Fatemeh. FREQUENCY AND CAUSES OF HYPOTONIA IN NEONATAL PERIOD WITH THE GESTATIONAL AGE OF MORE THAN 36 WEEKS IN NICU OF MOFID CHILDREN HOSPITAL, TEHRAN, IRAN DURING 2012-2014. IRANIAN JOURNAL OF CHILD NEUROLOGY (IJCN)[Internet]. 2017;11(1):0-0. Available from: https://sid.ir/paper/303520/en

IEEE: Copy

NOSRATOLLAH SEYED SHAHABI, Hossain FAKHRAEE, MOHAMMAD KAZEMIAN, Abolfazl Afjeh, MINOO FALLAHI, MARYAM SHARIATI, and Fatemeh GORJI, “FREQUENCY AND CAUSES OF HYPOTONIA IN NEONATAL PERIOD WITH THE GESTATIONAL AGE OF MORE THAN 36 WEEKS IN NICU OF MOFID CHILDREN HOSPITAL, TEHRAN, IRAN DURING 2012-2014,” IRANIAN JOURNAL OF CHILD NEUROLOGY (IJCN), vol. 11, no. 1, pp. 0–0, 2017, [Online]. Available: https://sid.ir/paper/303520/en

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