HUMAN HERPES VIRUS TYPE 6 AND FEBRILE CONVULSION

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HOOSHMANDI MOHAMMAD MEHDI; MOAYEDI ALIREZA; RAHMATI MOHAMMAD BAGHER; NAZEMI GHESHMI ABDOLMAJID; FAKHRAI DARIOUSH; ZARE SHAHRAM

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Journal: Iranian Journal of Child Neurology Year:2015 | Volume:9 | Issue:4 Page(s): 10-14

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Title

HUMAN HERPES VIRUS TYPE 6 AND FEBRILE CONVULSION

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Keywords

HHV-6

CHILDREN

FEBRILE CONVULSION

Abstract

Objective FEBRILE CONVULSION (FC) is occurred in 6 months to 5 yr old CHILDREN. The aim of this study was to investigate the prevalence of HHV-6 infection in FC admitted patients of Bandar Abbas CHILDREN Hospital, southern Iran.Materials & Methods In a cross-sectional study, 118 CHILDREN aged 6-60 months who had FC were selected by a simple random method in 2010-11. Demographic data, clinical manifestation and two blood samples gathered to assess the human herpes virus type 6 (HHV6). Blood sample obtained at the time of admission and 10 days after the first examination. ELISA was used to detect HHV-6 IgG. The subjects were studied in two groups with and without infection of HHV-6. Two groups were compared by t-test and X2.Results Fifty-three subjects completed the study, including 30 boys (56.6 %) and 23 girls (43.4%). The HHV-6 infection was detected in 23 patients out of 53 studied subjects. The mean of age for the groups with and without HHV-6 infection was 19.7±9.7 and 20.4±10.2 months old, respectively. The most common clinical presentation in both groups was rhinorrhea, diarrhea, vomiting and lethargy without any significant difference between two groups. Five patients (21.7%) in HHV-6 group and 1 patient (3.3%) in HHV-6 negative group had postictal phase more than 15 minutes (P<0.05). Convulsion within 1 hour from beginning of fever was more frequent in HHV-6 infection group than the other group (P<0.01).Conclusion There was not any difference in terms of age group, gender and clinical manifestation of infected and non-infected CHILDREN with FC. Postictal phase and seizure during 1 hour after the fever were significantly different between two groups.

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APA: Copy

HOOSHMANDI, MOHAMMAD MEHDI, MOAYEDI, ALIREZA, RAHMATI, MOHAMMAD BAGHER, NAZEMI GHESHMI, ABDOLMAJID, FAKHRAI, DARIOUSH, & ZARE, SHAHRAM. (2015). HUMAN HERPES VIRUS TYPE 6 AND FEBRILE CONVULSION. IRANIAN JOURNAL OF CHILD NEUROLOGY (IJCN), 9(4), 10-14. SID. https://sid.ir/paper/303586/en

Vancouver: Copy

HOOSHMANDI MOHAMMAD MEHDI, MOAYEDI ALIREZA, RAHMATI MOHAMMAD BAGHER, NAZEMI GHESHMI ABDOLMAJID, FAKHRAI DARIOUSH, ZARE SHAHRAM. HUMAN HERPES VIRUS TYPE 6 AND FEBRILE CONVULSION. IRANIAN JOURNAL OF CHILD NEUROLOGY (IJCN)[Internet]. 2015;9(4):10-14. Available from: https://sid.ir/paper/303586/en

IEEE: Copy

MOHAMMAD MEHDI HOOSHMANDI, ALIREZA MOAYEDI, MOHAMMAD BAGHER RAHMATI, ABDOLMAJID NAZEMI GHESHMI, DARIOUSH FAKHRAI, and SHAHRAM ZARE, “HUMAN HERPES VIRUS TYPE 6 AND FEBRILE CONVULSION,” IRANIAN JOURNAL OF CHILD NEUROLOGY (IJCN), vol. 9, no. 4, pp. 10–14, 2015, [Online]. Available: https://sid.ir/paper/303586/en

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